5-HYDROXY-2'-DEOXYURIDINE
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- CAS号:
- 5168-36-5
- 英文名:
- 5-HYDROXY-2'-DEOXYURIDINE
- 英文别名:
- 5-OHdU;Oh-5-du;5-HYDROXY-2'-DEOXYURIDINE;2'-Deoxy-5-hydroxyuridine;5-HYDROXY-2'-DEOXYURIDINE;2'-DEOXY-5-HYDROXY-D-URIDINE;Uridine, 2'-deoxy-5-hydroxy-
- 中文名:
- 5-HYDROXY-2'-DEOXYURIDINE
- 中文别名:
- 化合物 T19152;2'-脱氧-5-羟基尿苷;2'-脱氧-5-羟基尿苷;5-羟基-2'-脱氧尿苷
- CBNumber:
- CB7403475
- 分子式:
- C9H12N2O6
- 分子量:
- 244.2
- MOL File:
- 5168-36-5.mol
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5-HYDROXY-2'-DEOXYURIDINE化学性质
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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Methanol (Slightly, Heated, Sonicated), Water (Slightly)
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形态:
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Solid
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颜色:
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White to Off-White
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水溶解性:
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Water: 10 mg/mL (40.95 mM)
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稳定性:
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Hygroscopic
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5-HYDROXY-2'-DEOXYURIDINE性质、用途与生产工艺
5-Hydroxy-2'-deoxyuridine (5-OHdU) 是一种 2'-Deoxycytidine 的主要稳定氧化产物。5-Hydroxy-2'-deoxyuridine 可以通过 DNA 聚合酶在体外掺入 DNA。
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Human Endogenous Metabolite
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To study the specificity of nucleotide incorporation opposite 5-hydroxypyrimidines in template DNA, 18- and 45-member oligodeoxyribonucleotides, containing an internal 2'-deoxy-5-hydroxyuridine (5-OHdU) in two different sequence contexts, were used. Translesion synthesis past 2'-deoxy-5-hydroxyuridine (5-OHdU) in both oligonucleotides occurred, but pauses both opposite, and one nucleotide prior to, the modified base in the template is observed. The specificity of nucleotide incorporation opposite 2'-deoxy-5-hydroxyuridine (5-OHdU) in the template is sequence context dependent. In one sequence context, dA is the principal nucleotide incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU). However in a second sequence context, dC is the predominant base incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU). In that same sequence context, dC is also the predominant nucleotide incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU).
5-HYDROXY-2'-DEOXYURIDINE
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-130801 | 5-Hydroxy-2'-deoxyuridine | | 5 mg | 900元 |
| 2024/04/30 | HY-130801 | 5-HYDROXY-2'-DEOXYURIDINE
5-Hydroxy-2'-deoxyuridine | 5168-36-5 | 10 mM * 1 mLin DMSO | 990元 |
5-HYDROXY-2'-DEOXYURIDINE
生产厂家
5168-36-5, 5-HYDROXY-2'-DEOXYURIDINE 相关搜索:
- 抑制剂
- 2'-脱氧-5-羟基尿苷
- 2'-脱氧-5-羟基尿苷
- 化合物 T19152
- 5-羟基-2'-脱氧尿苷
- 5168-36-5
- 5-HYDROXY-2'-DEOXYURIDINE
- 5-OHdU
- 2'-DEOXY-5-HYDROXY-D-URIDINE
- 2'-Deoxy-5-hydroxyuridine
- Uridine, 2'-deoxy-5-hydroxy-
- Oh-5-du
- 5-HYDROXY-2'-DEOXYURIDINE