阿托伐他汀(3R,5S)-异构体钠
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- CAS号:
- 131275-93-9
- 英文名:
- Atorvastatin 10-Trans (Atorvastatin Impurity AT10)
- 英文别名:
- Atorvastatin SodiuM(EP);Atorvastatin Impurity AT10;(3R,5S)-Atorvastatin sodium;(3R,5S)-Atorvastatin Calcium;(3S,5R)-Atorvastatin Sodium Salt;Atorvastatin (3R,5S)-isomer Impurity;Atorvastatin (3R,5S)-IsoMer SodiuM Salt;Atorvastatin (3R,5S)-Isomer Calcium Salt;Atorvastatin 10-Trans (Atorvastatin Impurity AT10);[R-(R*,S*)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-he
- 中文名:
- 阿托伐他汀(3R,5S)-异构体钠
- 中文别名:
- (3R,5S)-阿托伐他汀;(3R,5S)-阿托伐他汀钠盐;阿托伐他汀(3R,5S)杂质钙盐;阿托伐他汀(3R,5S)-异构体钠;阿托伐他汀(3R,5S)-异构体钠盐;R.(R. .R:)-2-(4氟苯基)-B.0二羟基-5-(1-甲基乙基):3-茎基[(茎胺基)羟基)-1H-吡咯- 1.-庚酸钠盐
- CBNumber:
- CB91872919
- 分子式:
- C33H34FN2O5.Na
- 分子量:
- 580.629
- MOL File:
- 131275-93-9.mol
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阿托伐他汀(3R,5S)-异构体钠化学性质
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熔点:
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178-180°C
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储存条件:
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Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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溶解度:
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Methanol (Slightly), Water (Slightly)
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形态:
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Solid
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颜色:
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White to Off-White
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稳定性:
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Hygroscopic
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阿托伐他汀(3R,5S)-异构体钠性质、用途与生产工艺
(3R,5S)-Atorvastatin sodium 是 Atorvastatin 的杂质。Atorvastatin 是一种口服活性的 HMG-CoA 还原酶抑制剂，具有有效降低血脂的能力。Atorvastatin 以 IC50 分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 增殖和侵袭。
阿托伐他汀(3R,5S)-异构体钠
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上游原料
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131275-93-9, 阿托伐他汀(3R,5S)-异构体钠 相关搜索:
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Impurities
- Pfizer compounds
- Inhibitors
- Chiral Reagents
- Aromatics
- 活性氧
- 杂质
- 中间体
- R.(R. .R:)-2-(4氟苯基)-B.0二羟基-5-(1-甲基乙基):3-茎基[(茎胺基)羟基)-1H-吡咯- 1.-庚酸钠盐
- (3R,5S)-阿托伐他汀钠盐
- 阿托伐他汀(3R,5S)杂质钙盐
- (3R,5S)-阿托伐他汀
- 阿托伐他汀(3R,5S)-异构体钠盐
- 阿托伐他汀(3R,5S)-异构体钠
- 131275-93-9
- Atorvastatin (3R,5S)-isomer Impurity
- (3R,5S)-Atorvastatin sodium
- Atorvastatin (3R,5S)-Isomer Calcium Salt
- (3R,5S)-7-[3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid sodium salt
- sodium,(3R,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
- Atorvastatin (3R,5S)-IsoMer SodiuM Salt
- Atorvastatin SodiuM(EP)
- [R-(R*,S*)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-he
- (βS,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM Salt
- (βR,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM Salt
- (3S,5R)-Atorvastatin Sodium Salt
- (3R,5S)-Atorvastatin Calcium
- Atorvastatin Impurity AT10
- Atorvastatin 10-Trans (Atorvastatin Impurity AT10)
- [R-(R*,S*)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt