NSC 33994
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- CAS号:
- 82058-16-0
- 英文名:
- NSC 33994
- 英文别名:
- G6;NSC 33994;4,4′-(3E)-Hex-3-ene-3,4-diylbis{2-[(diethylamino)methyl]phenol};(E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylaMino)Methyl]phenol;4,4'-[(1E)-1,2-Diethyl-1,2-ethenediyl]bis[2-[(diethylaMino)Methyl]phenol;Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis[2-[(diethylamino)methyl]-;(E)-4,4′-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]-phenol (9CI)
- 中文名:
- NSC 33994
- 中文别名:
- 化合物 T23091
- CBNumber:
- CB92550801
- 分子式:
- C28H42N2O2
- 分子量:
- 438.65
- MOL File:
- 82058-16-0.mol
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NSC 33994化学性质
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沸点:
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524.7±45.0 °C(Predicted)
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密度:
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1.040±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMSO: ≥25mg/mL
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形态:
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powder
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酸度系数(pKa):
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9.20±0.50(Predicted)
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颜色:
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white to tan
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稳定性:
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Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
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NSC 33994性质、用途与生产工艺
NSC 33994 (G6) 是选择性的 JAK2 抑制剂，其 IC50 值为 60 nM。
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JAK2
60 nM (IC
50
, JAK2 Val617Phe kinase activity )
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NSC 33994 (G6) reduces the levels of phospho-JAK2 in both a dose- and time-dependent manner.
NSC 33994 (G6, 0-25 μM, 0-48 h) inhibits phospho-JAK2 (pY1007/pY1008) in a dose-dependent and time-dependent manner.
NSC 33994
上下游产品信息
上游原料
下游产品
82058-16-0, NSC 33994 相关搜索:
- Intracellular signaling.
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Inhibitors
- Aromatics
- Amines
- 化合物 T23091
- 82058-16-0
- Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis[2-[(diethylamino)methyl]-
- NSC 33994
- G6
- 4,4′-(3E)-Hex-3-ene-3,4-diylbis{2-[(diethylamino)methyl]phenol}
- (E)-4,4′-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]-phenol (9CI)
- 4,4'-[(1E)-1,2-Diethyl-1,2-ethenediyl]bis[2-[(diethylaMino)Methyl]phenol
- (E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylaMino)Methyl]phenol