VUF10460
|
|
|
- CAS号:
- 1028327-66-3
- 英文名:
- VUF 10460
- 英文别名:
- VUF 10460;VUF 10460;VUF-10460;4-(4-Methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine;4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine;2-Pyrimidinamine, 4-(4-methyl-1-piperazinyl)-6-phenyl-;VUF10460,Inhibitor,VUF 10460,inhibit,Histamine Receptor,VUF-10460
- 中文名:
- VUF10460
- 中文别名:
- 化合物VUF10460;VUF10460游离态;VUF 10460,H4激动剂;4-(4-甲基哌嗪-1-基)-6-苯基嘧啶-2-胺
- CBNumber:
- CB93037581
- 分子式:
- C15H19N5
- 分子量:
- 269.34
- MOL File:
- 1028327-66-3.mol
|
|
|
VUF10460化学性质
-
沸点:
-
523.8±60.0 °C(Predicted)
-
|
-
密度:
-
1.187±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
under inert gas (nitrogen or Argon) at 2–8 °C
-
|
-
溶解度:
-
DMSO: 100mg/mL
-
|
-
形态:
-
Powder
-
|
-
酸度系数(pKa):
-
7.86±0.10(Predicted)
-
|
VUF10460性质、用途与生产工艺
VUF10460是histamine H4 receptor激动剂。
UF10460 binds to rat H3 and H4 receptor with pK
i
values of 5.75, and 7.46, respectively. VUF10460 displays approximately a 50-fold selectivity for the rat H4 receptor over the H3 receptor.
HCl-induced rat gastric lesions is significantly enhanced by the H4 receptor agonists VUF10460. This effect is not modified by H4 receptor antagonist JNJ7777120.
VUF10460
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-101420 | VUF10460
VUF10460 | 1028327-66-3 | 5mg | 950元 |
| 2024/04/30 | S6569 | VUF10460
VUF10460 | 1028327-66-3 | 5mg | 958.34元 |
1028327-66-3, VUF10460 相关搜索:
- 药靶配体
- VUF 10460,H4激动剂
- 4-(4-甲基哌嗪-1-基)-6-苯基嘧啶-2-胺
- 化合物VUF10460
- VUF10460游离态
- 1028327-66-3
- 4-(4-Methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
- VUF10460,Inhibitor,VUF 10460,inhibit,Histamine Receptor,VUF-10460
- 2-Pyrimidinamine, 4-(4-methyl-1-piperazinyl)-6-phenyl-
- VUF 10460;VUF-10460
- 4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine
- VUF 10460