1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮
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- CAS号:
- 16616-39-0
- 英文名:
- 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
- 英文别名:
- MLS-532223;MLS000532223;1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one;1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one;2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-;GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit
- 中文名:
- 1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮
- 中文别名:
- 化合物MLS000532223;1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮
- CBNumber:
- CB96188330
- 分子式:
- C15H9NO3
- 分子量:
- 251.24
- MOL File:
- 16616-39-0.mol
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1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮化学性质
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熔点:
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120-121 °C
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沸点:
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419.6±47.0 °C(Predicted)
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密度:
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1.31±0.1 g/cm3(Predicted)
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储存条件:
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RT (des.)
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溶解度:
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Soluble in DMSO (up to 20 mg/ml).
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形态:
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solid
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颜色:
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Beige
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稳定性:
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Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
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1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮性质、用途与生产工艺
MLS000532223 是一种 Rho family GTPases 的高亲和力的选择性抑制剂,EC50值为16 μM至120 μM。
Target | Value |
Rho
(Cell-free assay)
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16 μM(EC50)
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MLS000532223 prevents GTP binding to several GTPases in a dose-dependent manner.
MLS000532223 modulates Rho-family GTP-binding kinetics.
MLS000532223 is active in cell-based assays and inhibits EGF-stimulated Rac 1 activation.
MLS000532223 inhibits actin rearrangements and changes in cell morphology that are downstream of Rho family GTPase activation.
MLS000532223 (10 μM) modulates actin remodeling in mast cells.
MLS000532223 (10 μM) inhibits ligand-stimulated β-hexosaminidase secretion of RBL cells.
1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/04/30 | HY-117149 | MLS000532223 | | 1 mg | 1200元 |
2024/04/30 | HY-117149 | 1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮 MLS000532223 | 16616-39-0 | 5mg | 3000元 |
1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮
生产厂家
16616-39-0, 1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮 相关搜索:
- 药靶配体
- 化合物MLS000532223
- 1-(3-硝基苯基)-3-苯基丙-2-炔-1-酮
- 16616-39-0
- GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit
- MLS-532223
- 1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one
- 2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-
- MLS000532223
- 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one