2-甲基-2,6-壬二烯-1-胺
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- CAS号:
- 96-88-8
- 英文名:
- N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
- 英文别名:
- C07528;Carbocain;Polocaine;Mepicaine;Carbocaine;Scandicain;Scandicaine;DL-Mepivacaine;1-Methyl-2',6'-pipecoloxylidide;Mepivacaine (base and/or unspecified salts)
- 中文名:
- 2-甲基-2,6-壬二烯-1-胺
- 中文别名:
- 美哌卡因;6-壬二烯-1-胺;2-甲基-2,6-壬二烯-1-胺;N-(2,6-二甲基苯基)-1-甲基哌啶-2-酰胺;N-(26-二甲基苯基)-1-甲基哌啶-2-甲酰胺
- CBNumber:
- CB9907386
- 分子式:
- C15H22N2O
- 分子量:
- 246.35
- MOL File:
- 96-88-8.mol
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2-甲基-2,6-壬二烯-1-胺化学性质
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熔点:
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150-151°
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沸点:
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389.35°C (rough estimate)
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密度:
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0.9978 (rough estimate)
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折射率:
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1.6280 (estimate)
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储存条件:
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Store at -20°C
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溶解度:
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DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
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形态:
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A crystalline solid
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酸度系数(pKa):
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14.85±0.70(Predicted)
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水溶解性:
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2.217g/L(25 ºC)
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EPA化学物质信息:
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2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl- (96-88-8)
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2-甲基-2,6-壬二烯-1-胺性质、用途与生产工艺
Mepivacaine 是一种酰胺型药剂，可暂时使局部失去知觉。Mepivacaine 与神经元细胞膜上特定的电压门控钠离子通道结合，抑制钠离子内流和膜去极化。
Mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.
Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine).
Mepivacaine displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels.
2-甲基-2,6-壬二烯-1-胺
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | S5392 | 2-甲基-2,6-壬二烯-1-胺
Mepivacaine | 96-88-8 | 25mg | 794.84元 |
96-88-8, 2-甲基-2,6-壬二烯-1-胺 相关搜索:
- research chemical
- 合成有机化合物配体
- 药物杂质及中间体
- N-(2,6-二甲基苯基)-1-甲基哌啶-2-酰胺
- 美哌卡因
- N-(26-二甲基苯基)-1-甲基哌啶-2-甲酰胺
- 6-壬二烯-1-胺
- 2-甲基-2,6-壬二烯-1-胺
- 96-88-8
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-
- C07528
- DL-1-METHYL-2'',6''-PIPECOLINOXYLIDIDE(MEPIVACAINE BASE)
- Mepivacaine (base and/or unspecified salts)
- Scandicaine
- Scandicain
- Mepicaine
- DL-Mepivacaine
- Carbocaine
- Carbocain
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl- (9CI)
- 2',6'-Pipecoloxylidide, 1-methyl- (6CI, 8CI)
- 1-Methyl-2',6'-pipecoloxylidide
- Polocaine