Alantolactone
- CAS No.
- 546-43-0
- Chemical Name:
- Alantolactone
- Synonyms
- HELENINE;ALANTOLACETONE;Alantolactone/Helenine;4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone;helenin;Eupatal;NSC 93131;NSC 333843;Alant camphor;ALANTOLACTONE
- CBNumber:
- CB0194433
- Molecular Formula:
- C15H20O2
- Molecular Weight:
- 232.32
- MDL Number:
- MFCD00274568
- MOL File:
- 546-43-0.mol
| Melting point | 78-79 C |
|---|---|
| Boiling point | 275 C |
| alpha | D +175° (chloroform) |
| Density | 1.0610 (rough estimate) |
| refractive index | 1.4360 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: soluble15mg/mL (clear solution) |
| form | powder |
| color | white to beige |
| LogP | 3.380 |
| CAS DataBase Reference | 546-43-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | M7GSN5Q1M6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261-P272-P280-P333+P313-P362+P364-P501 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-36-36/37-24/25 |
| WGK Germany | 3 |
| HS Code | 29322090 |
Alantolactone price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0415 | Alantolactone ≥98% (HPLC) | 546-43-0 | 5mg | $67.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0415 | Alantolactone ≥98% (HPLC) | 546-43-0 | 25mg | $441 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL89156 | Alantolactone phyproof? Reference Substance | 546-43-0 | 10MG | $430 | 2024-03-01 | Buy |
| Cayman Chemical | 29762 | Alantolactone | 546-43-0 | 5mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 29762 | Alantolactone | 546-43-0 | 10mg | $116 | 2024-03-01 | Buy |
Alantolactone Chemical Properties,Uses,Production
Description
The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone-mix, used to detect sensitization to Compositae.
Chemical Properties
Crystalline powder
Uses
Alantolactone has been used:
- in cell viability assay
- to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
- in assessment of degranulation
Uses
Alantolactone is sesquiterpene lactone that possesses anti-inflammatory property. Alantolactone have been studied to be developed as a novel agent against human liver cancer.
Uses
anthelmintic, antibacterial, antineoplastic
Definition
ChEBI: A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.
Contact allergens
The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone mix used to detect sensitization to Compositae-Asteraceae.
storage
Store at -20°C
Alantolactone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Alantolactone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | Alantolactone
546-43-0
|
US $0.00 / kg | 1kg | 98% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2024-04-02 | Alantolactone
546-43-0
|
US $580.00 / g | 1g | 97 | 500 Kg | R&D Scientific Inc. | |
 |
2023-08-22 | Alantolactone
546-43-0
|
US $50.00 / kg | 1kg | 99.9% | 10000tons | Anhui Ruihan Technology Co., Ltd |
-
- Alantolactone
546-43-0
- US $0.00 / kg
- 98%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Alantolactone
546-43-0
- US $580.00 / g
- 97
- R&D Scientific Inc.
-
- Alantolactone
546-43-0
- US $50.00 / kg
- 99.9%
- Anhui Ruihan Technology Co., Ltd
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