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Filipin II

CAS No.
38620-77-8
Chemical Name:
Filipin II
Synonyms
Filipin Ⅱ;Filipin II;(3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-Octahydroxy-3-hexyl-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaene-2-one;Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,16,27-octahydroxy-3-hexyl-17,28-dimethyl-, (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-
CBNumber:
CB02165446
Molecular Formula:
C35H58O10
Molecular Weight:
638.83
MDL Number:
MOL File:
38620-77-8.mol
Last updated:2023-05-21 10:59:17

Filipin II Properties

Boiling point 882.7±65.0 °C(Predicted)
Density 1.124±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 12.79±0.70(Predicted)

Filipin II price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25521 Filipin II ≥95% 38620-77-8 500μg $249 2024-03-01 Buy
Cayman Chemical 25521 Filipin II ≥95% 38620-77-8 2.5mg $934 2024-03-01 Buy
Product number Packaging Price Buy
25521 500μg $249 Buy
25521 2.5mg $934 Buy

Filipin II Chemical Properties,Uses,Production

Uses

Filipin II is a minor component of the filipin complex, a family of pentaene antifungal metabolites first isolated from Streptomyces filipinensis and reported by researchers at Upjohn in 1955. Structurally, filipin II lacks the hydroxy moiety on the pentyl side chain and is more hydrophobic, eluting later than filipin III on reverse phase HPLC. Filipin II is a potent broad spectrum antifungal agent that also exhibits antitumor and antiviral activities and acts by binding cell membrane sterols, disrupting membrane integrity.

Filipin II Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-Octahydroxy-3-hexyl-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaene-2-one Filipin II Filipin Ⅱ Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,16,27-octahydroxy-3-hexyl-17,28-dimethyl-, (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)- 38620-77-8