(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine
- CAS No.
- 52659-54-8
- Chemical Name:
- (2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine
- Synonyms
- Andrangine;(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine;2H-Cyclopent[ij]indolo[2,3-a]oxireno[g]quinolizine, 12a-ethyl-1a,4,5,5a,10,10b,11,12,12a,12b-decahydro-, (1aR,5aS,10aR,10bS,12aS,12bS)- (9CI)
- CBNumber:
- CB02319801
- Molecular Formula:
- C19H24N2O
- Molecular Weight:
- 296.41
- MDL Number:
- MOL File:
- 52659-54-8.mol
(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine Chemical Properties,Uses,Production
Description
One of two alkaloids isolated from the leaves of Craspidospermum verticilliatum var. petiotare, this base also occurs in the leaves of Crioceras diptadeniij1oris. It yields colourless needles when crystallized from hexane and is laevorotatory with a specific rotation of [α]20D- 42° (c 1.0, CHC13). The ultraviolet spectrum in EtOH consists of two absorption maxima at 248 and 299 nm. The base has been characterized as the N-methyl derivative with m.p. 138°C and [α]20D + 60.5° (c 0.9, CHC13). The structure given has been established from chemical degradations and spectroscopic investigations.
References
Bruneton, Bouquet, Cave, Phytochem., 13, 1963 (1974)
Kan-Fan et at., Bull. Soc. Chim. Fr. (12 part 2), 2839 (1974)
(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine Preparation Products And Raw materials
Raw materials
Preparation Products
(2β,5α,12β,19α)-1-Demethyl-6β,7β-epoxyvallesamidine
Andrangine
2H-Cyclopent[ij]indolo[2,3-a]oxireno[g]quinolizine, 12a-ethyl-1a,4,5,5a,10,10b,11,12,12a,12b-decahydro-, (1aR,5aS,10aR,10bS,12aS,12bS)- (9CI)
52659-54-8