ChemicalBook >> CAS DataBase List >>PTP1B-IN-2
PTP1B-IN-2
- CAS No.
- 1919853-46-5
- Chemical Name:
- PTP1B-IN-2
- Synonyms
- MDK3465;PTP1B-IN-2;PTP1B inhibitor 2;PTP1B-IN-2;PTP1B INHIBITOR 2;Inhibitor,PTP-1B-IN-2,inhibit,PTP1BIN2,Phosphatase,PTP1B IN 2;Benzoic acid, 5-[[[4-[(2-methoxy-2-oxoethyl)(methylsulfonyl)amino]phenyl]methyl][(phenylmethyl)sulfonyl]amino]-2-[(4-methylphenyl)methoxy]-, methyl ester
- CBNumber:
- CB03309540
- Molecular Formula:
- C34H36N2O9S2
- Molecular Weight:
- 680.79
- MDL Number:
- MOL File:
- 1919853-46-5.mol
Last updated:2023-05-21 10:59:17
PTP1B-IN-2 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-6881 | PTP1B-IN-2 99.85% | 1919853-46-5 | 100mg | $2520 | 2021-12-16 | Buy |
Ambeed | A949653 | PTP1B-IN-2 98% | 1919853-46-5 | 1mg | $63 | 2021-12-16 | Buy |
Crysdot | CD38000036 | PTP1B-IN-2 98% | 1919853-46-5 | 1mg | $105 | 2021-12-16 | Buy |
Ambeed | A949653 | PTP1B-IN-2 98% | 1919853-46-5 | 5mg | $107 | 2021-12-16 | Buy |
Ambeed | A949653 | PTP1B-IN-2 98% | 1919853-46-5 | 10mg | $139 | 2021-12-16 | Buy |
PTP1B-IN-2 Chemical Properties,Uses,Production
Biological Activity
PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B) with IC50 of 50 nM. It enhances insulin-mediated phosphorylation of insulin receptor beta (IRβ) and insulin-stimulated glucose uptake.
in vitro
PTP1B-IN-2 displays more than 40-fold selectivity for PTP1B over SHP-2 and LAR and 15-fold higher selectivity for PTP1B over the highly homologous TCPTP.
target
Target | Value |
PTP1B (Cell-free assay) | 50 nM |
PTP1B-IN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 49)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18218 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
1919853-46-5(PTP1B-IN-2)Related Search:
PTP1B-IN-2
MDK3465
PTP1B inhibitor 2
PTP1B-IN-2;PTP1B INHIBITOR 2
Inhibitor,PTP-1B-IN-2,inhibit,PTP1BIN2,Phosphatase,PTP1B IN 2
Benzoic acid, 5-[[[4-[(2-methoxy-2-oxoethyl)(methylsulfonyl)amino]phenyl]methyl][(phenylmethyl)sulfonyl]amino]-2-[(4-methylphenyl)methoxy]-, methyl ester
1919853-46-5