ChemicalBook >> CAS DataBase List >>DICHLORISONE ACETATE
DICHLORISONE ACETATE
- CAS No.
- 79-61-8
- Chemical Name:
- DICHLORISONE ACETATE
- Synonyms
- Sch 5005;DICHLORISONE ACETATE;dichlorisone 21-acetate;21-Acetyloxy-9,11β-dichloro-17-hydroxypregna-1,4-diene-3,20-dione;1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE;9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate;1,4-PREGNADIEN-9-ALPHA, 11-BETA-DICHLORO-17,21-DIOL-3,20-DIONE 21-ACETATE;inhibit,Inhibitor,Dichlorisone,Endogenous Metabolite,Dichlorisone Acetate;Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11b)-;Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11β)-
- CBNumber:
- CB0339584
- Molecular Formula:
- C23H28Cl2O5
- Molecular Weight:
- 455.37
- MDL Number:
- MFCD00133265
- MOL File:
- 79-61-8.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
| Melting point | 246-253 °C (decomp) |
|---|---|
| Boiling point | 596.2±50.0 °C(Predicted) |
| alpha | D25 +162° (dioxane) |
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 4.35 mg/mL (9.55 mM); Water: < 0.1 mg/mL (insoluble) |
| pka | 11.94±0.70(Predicted) |
| FDA UNII | 64FTA4579H |
DICHLORISONE ACETATE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-7866 | Dichlorisone acetate 99.77% | 79-61-8 | 10mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-7866 | Dichlorisone acetate 99.77% | 79-61-8 | 50mg | $108 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0000402 | DICHLORISONE ACETATE 95.00% | 79-61-8 | 500MG | $597.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0000402 | DICHLORISONE ACETATE 95.00% | 79-61-8 | 1G | $695.39 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0000402 | DICHLORISONE ACETATE 95.00% | 79-61-8 | 5G | $1050.24 | 2021-12-16 | Buy |
DICHLORISONE ACETATE Chemical Properties,Uses,Production
Originator
Diloderm ,Schering,US,1960
Uses
antipruretic
Definition
ChEBI: Dichlorisone is a corticosteroid hormone.
Manufacturing Process
A solution of 1.0 g of 1,4,9(11)-pregnatriene-17α,21-diol-3,20-dione-21-
acetate and 5.0 g of lithium chloride in 40 ml of glacial acetic acid is treated
with 0.410 g of N-chlorosuccinimide, followed by 0.104 g of anhydrous
hydrogen chloride dissolved in 2.5 ml of tetrahydrofuran. The reaction mixture
is stirred for 2 hours and poured into ice water. The crude product is filtered
and washed with water to give 1.12 g of solid material, which is recrystallized
from acetone-hexane to give substantially pure 9α,11β-dichloro-1,4-
pregnadiene-17α,21-diol-3,20-dione-21-acetate; MP 246°C to 253°C (dec.).
brand name
Diloderm (Schering).
Therapeutic Function
Antipruritic, Antihistaminic, Appetite stimulant
DICHLORISONE ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
DICHLORISONE ACETATE Suppliers
Global( 33)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7433 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Target molecule Corp. | 857-239-0968 | service1@targetmol.com | United States | 2559 | 60 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | chenjw@absin.cn | China | 24734 | 58 |
79-61-8(DICHLORISONE ACETATE)Related Search:
2-CHLORO-2,3-DIMETHYL BUTANE
6-Chlorohexanol
6-Chloro-2-hexanone
1-Chlorotetradecane
6-Chlorohex-1-ene
1-CHLORO-1-METHYLCYCLOHEXANE
1,6-Dichlorohexane
(R)-5-CHLORO-2-PENTANOL
1,10-Dichlorodecane
1,9-DICHLORONONANE
1of4
9ALPHA,11BETA-DICHLORO-17ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 21-ACETATE
1,4-PREGNADIEN-9-ALPHA, 11-BETA-DICHLORO-17,21-DIOL-3,20-DIONE 21-ACETATE
dichlorisone 21-acetate
9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate
21-Acetyloxy-9,11β-dichloro-17-hydroxypregna-1,4-diene-3,20-dione
Sch 5005
[2-[(9R,17R)-9,11-dichloro-17-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
[2-[(9R,17R)-9,11-dichloro-17-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate
acetic acid [2-[(9R,17R)-9,11-dichloro-17-hydroxy-3-keto-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
DICHLORISONE ACETATE
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11β)-
Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9,11-dichloro-17-hydroxy-, (11b)-
inhibit,Inhibitor,Dichlorisone,Endogenous Metabolite,Dichlorisone Acetate
1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE
79-61-8
C23H28Cl2O5
Inhibitors
DILODERM