ChemicalBook >> CAS DataBase List >>trans-1,2-Cyclohexanedicarboxylic acid
trans-1,2-Cyclohexanedicarboxylic acid
- CAS No.
- 2305-32-0
- Chemical Name:
- trans-1,2-Cyclohexanedicarboxylic acid
- Synonyms
- TRANS-HEXAHYDRO-PHTHALIC ACID;TRANS-CYCLOHEXANE-1,2-DICARBOXYLIC ACID;trans-Cyclohexane-1,2-dicarboxylic acid, trans-Hexahydrophthalic acid;Lura;trans-CycL;REMAINDER CIS;RSYY（Avanafil)-15;ohexane-1,2-dicarboxyL;Lurasidone InterMediate(1);1,2-cyclohexanedicarboxylic
- CBNumber:
- CB0376262
- Molecular Formula:
- C8H12O4
- Molecular Weight:
- 172.18
- MDL Number:
- MFCD00001464
- MOL File:
- 2305-32-0.mol
- MSDS File:
- SDS
Last updated:2024-05-29 17:03:55
| Melting point | 228-230 °C (lit.) |
|---|---|
| Boiling point | 262.49°C (rough estimate) |
| Density | 1.2104 (rough estimate) |
| refractive index | 1.4450 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | Acetone (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | pK1:4.18;pK2: 5.93 (20°C) |
| color | White |
| Water Solubility | 2g/L(20 ºC) |
| BRN | 3200609 |
| InChIKey | QSAWQNUELGIYBC-WDSKDSINSA-N |
| CAS DataBase Reference | 2305-32-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,2-Cyclohexanedicarboxylic acid, trans-(2305-32-0) |
| EPA Substance Registry System | 1,2-Cyclohexanedicarboxylic acid, (1R,2R)-rel- (2305-32-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GU9065000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29172000 | |||||||||
| NFPA 704 |
|
trans-1,2-Cyclohexanedicarboxylic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.41088 | trans-Cyclohexane-1,2-dicarboxylic acid for synthesis | 2305-32-0 | 5G | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | 147516 | trans-1,2-Cyclohexanedicarboxylic acid 95% | 2305-32-0 | 25g | $311 | 2023-01-07 | Buy |
| TCI Chemical | C0474 | trans-1,2-Cyclohexanedicarboxylic Acid >98.0%(GC)(T) | 2305-32-0 | 25g | $129 | 2024-03-01 | Buy |
| TCI Chemical | C0474 | trans-1,2-Cyclohexanedicarboxylic Acid >98.0%(GC)(T) | 2305-32-0 | 500g | $1217 | 2024-03-01 | Buy |
| Alfa Aesar | L11288 | trans-1,2-Cyclohexanedicarboxylic acid 98% | 2305-32-0 | 5g | $56.65 | 2024-03-01 | Buy |
trans-1,2-Cyclohexanedicarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
trans-1,2-cyclohexanedicarboxylic acid be used as organic intermediates.
Uses
trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.
Purification Methods
It is purified by recrystallisation from EtOH or H2O. It is formed by hydrolyzing the anhydride with water. The dimethyl ester has m 95-96o (from *C6H6/pet ether). [Abell J Org Chem 22 769 1957, Smith & Byrne J Am Chem Soc 72 4406 1950, Linstead et al. J Am Chem Soc 64 2093 1942, Beilstein 9 III 3812, 9 IV 2801.] The 1R,2R-(-)-trans-cyclohexane-1,2-acid [46022-05-3] has m 171-182o and [ ] D -20o (c 1, Me2CO). cis-Cyclohexane-1,2-dicarboxylic anhydride (cis-hexahydrophthalic anhydride) [85-42-7, 13149-00-3] M 154.2, m 32-34o, b 158o/17mm. It has been obtained by heating the trans-acid or anhydride at 200o. Crystallise it from *C6H6/Et2O or distil it. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Abell J Org Chem 22 769 1957, Beilstein 17 II 452, 17 III/IV 5931.]
trans-1,2-Cyclohexanedicarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 292)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12468 | 58 |
| Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15664 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15956 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21688 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | info@pharmachemm.com | China | 225 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8829 | 58 |
View Lastest Price from trans-1,2-Cyclohexanedicarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-29 | trans-1,2-Cyclohexanedicarboxylic acid
2305-32-0
|
US $10.00 / kg | 1kg | 99% | 20tons | Hebei Duling International Trade Co. LTD | |
 |
2023-08-30 | trans-1,2-Cyclohexanedicarboxylic acid
2305-32-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2021-08-12 | trans-1,2-Cyclohexanedicarboxylic acid
2305-32-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- trans-1,2-Cyclohexanedicarboxylic acid
2305-32-0
- US $10.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
-
- trans-1,2-Cyclohexanedicarboxylic acid
2305-32-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- trans-1,2-Cyclohexanedicarboxylic acid
2305-32-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
2305-32-0(trans-1,2-Cyclohexanedicarboxylic acid)Related Search:
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trans,trans-2,4-Undecadienal
Cyclohexane
(3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione
(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL
1of4
trans-Cyclohexane-1,2-dicarboxylic acid for synthesis
TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ACID
TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ACID, 95%, REMAINDER CIS
rel-(1R*)-1β*,2α*-Cyclohexanedicarboxylic acid
rel-(1R*,2R*)-1,2-Cyclohexanedicarboxylic acid
rel-Cyclohexane-1β*,2α*-dicarboxylic acid
trans-1,2-Cyclohexanedicarboxylic acid, remainder cis, 95%
TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ACDI
Trans-1,2-cyclohexane carboxylic acid
1,2-cyclohexanedicarboxylic
1,2-Cyclohexanedicarboxylicacid, (1R,2R)-rel-
trans-1,2-Cyclohexanedicarboxylic acid ,98%
Lurasidone InterMediate(1)
Lura
REMAINDER CIS
trans-1,2-Cyclohexanedicarboxylic acid, reMainder cis
TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ACDI
trans-1,2-Cyclohexanedicarboxylic acid
trans-1,2-Cyclohexanedicarboxylic acid 95%
(1S,2S)-2-Carbamoyl-cyclohexanecarboxylic acid
trans-1,2-Cyclohexanedicarboxylic Acid >
ohexane-1,2-dicarboxyL
trans-CycL
rans-1,2-Cyclohexanedicarboxylicaci
Trans-1,2-Cyclohexanedicarboxylic acid(For export only)
TRANS-HEXAHYDRO-PHTHALIC ACID
TRANS-CYCLOHEXANE-1,2-DICARBOXYLIC ACID
trans-Cyclohexane-1,2-dicarboxylic acid, trans-Hexahydrophthalic acid
RSYY（Avanafil)-15
2305-32-0
CARBOXYLIC ACID
Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts