Gibberellic acid
- CAS No.
- 77-06-5
- Chemical Name:
- Gibberellic acid
- Synonyms
- GA3;GIBBERELLIN;GIBBERELIC ACID;Gibberellic;Gibberellins;GIBBERELLIN A3;PRO-GIBB;GIBBERLIC ACID;RELEASE;GIBERELLIN
- CBNumber:
- CB0734590
- Molecular Formula:
- C19H22O6
- Molecular Weight:
- 346.38
- MDL Number:
- MFCD00079329
- MOL File:
- 77-06-5.mol
- MSDS File:
- SDS
| Melting point | 227 °C |
|---|---|
| Boiling point | 401.12°C (rough estimate) |
| alpha | 82.5 º (c=10, ethanol) |
| Density | 1.34 g/cm3 (20℃) |
| refractive index | 81 ° (C=2, MeOH) |
| storage temp. | 0-6°C |
| solubility | 5g/l |
| form | Powder |
| pka | 4.0(at 25℃) |
| color | White to pale yellow |
| optical activity | [α]20/D +80±3°, c = 1% in methanol |
| Water Solubility | 5 g/L (20 º C) |
| Merck | 14,4419 |
| BRN | 54346 |
| Stability | Stable. Combustible. Incompatible with acids, strong oxidizing agents. |
| InChIKey | IXORZMNAPKEEDV-OBDJNFEBSA-N |
| LogP | 0.240 |
| CAS DataBase Reference | 77-06-5 |
| EWG's Food Scores | 1 |
| FDA UNII | BU0A7MWB6L |
| NIST Chemistry Reference | Gibberellic acid(77-06-5) |
| EPA Substance Registry System | Gibberellic acid (77-06-5) |
| Pesticides Freedom of Information Act (FOIA) | Gibberellin |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280i-P337+P313-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| RIDADR | None [88] Not regulated. | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LY8990000 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29322980 | |||||||||
| Toxicity | LD50 orally in Rabbit: 6300 mg/kg LD50 dermal Rabbit > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Gibberellic acid price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.14464 | Gibberellic acid for synthesis | 77-06-5 | 500mg | $41 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.14464 | Gibberellic acid for synthesis | 77-06-5 | 1g | $42.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.14464 | Gibberellic acid for synthesis | 77-06-5 | 5G | $148 | 2024-03-01 | Buy |
| Sigma-Aldrich | 48880 | Gibberellic acid 90% gibberellin A3 basis (HPLC) | 77-06-5 | 250mg | $55.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 48880 | Gibberellic acid 90% gibberellin A3 basis (HPLC) | 77-06-5 | 1g | $72.4 | 2024-03-01 | Buy |
Gibberellic acid Chemical Properties,Uses,Production
Description
Gibberellic acid (GA) is a tetracyclic di-terpenoid compound. It is one of the major hormones that can be synthesized in plants and fungi. It has various kinds of physiological effects including stimulating seed germination, inducing mitotic division of the leaves, triggering transitions from meristem to shoot growth, vegetative to flowering, determining sex expression and grain development through crosstalk with many environmental signals such as light, temperature and water. In lab and greenhouse, it can be used to trigger germination of seeds which has previously remained dormant. It can also used to induce the production of larger amount and bigger grapes, boosting the grape industry. In industry, GA can be produced from Solid-state Fermentation (SSF) which can have relatively high yield.
Chemical Properties
white powder
Uses
Gibberellic Acid is a a pentacyclic diterpene acid. Gibberellic Acid is a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic acid acts as a plant growth reg ulator on account of its physiological and morphological effects in extremely low concentrations. Generally Gibberellic acid affects only the plant parts above the soil surface.
Uses
Gibberellic acid is used as a plant growth hormone. It is also used to trigger germination in dormant seeds in laboratory and green house settings and to stimulate rapid stem and root growth and induce mitotic division in the leaves of some plants. It also serves in grape growing industry as a hormone to induce the production of larger bundles and bigger grape.
Definition
ChEBI: A C19-gibberellin that is a pentacyclic diterpenoid responsible for promoting growth and elongation of cells in plants.
Biosynthesis
The presence of GA in actively growing tissues, i.e., shoot apices, young leaves, and flowers. Gibberellins (GAs; Gibberellic acids) being synthesized via the terpenoid pathway, require 3 enzymes viz., terpene synthase (TPSs), cytochrome P450 monooxygenase (P450s) and 2-oxoglutarate dependent dehydrogenase (2 ODDs), for the biosynthesis of bioactive GA from geranylgeranyl diphosphate in plants. Two terpene synthases, ent-copalyl diphosphate synthase (CPS) and ent-kaurene synthase (KS), located in plastids, are involved in the conversion of GGDP to tetracyclic hydrocarbon intermediate ent-kaurene. ent-Kaurene is then converted to GA12 by 2 P450s. First, ent-Kaurene oxidase (KO), present in the plastid's outer membrane, catalyzes the sequential oxidation of C-19 to produce ent-kaurenoic acid. Second, the kaurenoic acid oxidase (KAO) in the endoplasmic reticulum is converted to GA12. Bioactive GA4 is converted from GA12 through oxidations on C-20 and C-3 by GA 20-oxidase (GA20ox) and GA 3-oxidase (GA3ox)[3].
General Description
White powder.
Air & Water Reactions
Slightly water soluble .
Reactivity Profile
Gibberellic acid is readily degraded by acids. .
Fire Hazard
Flash point data for Gibberellic acid are not available. Gibberellic acid is probably combustible.
Agricultural Uses
Plant growth hormone, Plant regulator: Gibberellic acids (Gibberellins) are naturally occurring plant hormones that are used as plant growth regulators to stimulate both cell division and elongation that affects leaves and stems. Applications of this hormone also hastens plant maturation and seed germination. Delayed harvesting of fruits, allowing them to grow larger. Gibberellic acids are applied to growing field crops, small fruits, grapes, vines and tree fruit, and ornamentals, shrubs and vines.
Agricultural Uses
Gibberellin is a growth promoting substance found widely in plants. It was first isolated from the fungus Gibberella. Gibberellin increases the rate of photosynthesis and helps in the elongation of cells. It promotes the flowering and germination of plants. With a general formula of Cl9H22O6, gibberellins are also produced by Azotobacter, Azospirillum, etc.
Agricultural Uses
Gibberellic acid is an organic acid used as a plant growth hormone. It is formed by the fungus Gibberellafujikuroi in aerated submerged culture.
Trade name
ACTIVOL®; BERELEX®; BRELLIN®; BOLL-SET®; CEKUGIB®; CROP BOOSTER®; CYTOPLEX HMS®, DYNOGEN®; FALGRO®; FLORALTONE® (with 2,3,5-triiodobenzoic acid); FLORGIB®; FOLI-ZYME®; GIBBEX®; GIBBERELLIN A 3 ®; GIBBERELLIN X®; GIBBREL®; GIBGRO®; GIB-SOL®; GIB-TABS®; GIBRESCOL®; GROCEL®; KALGIBB®; MAXON®; N-LARGE®; NOVAGIB®; PGR-IV®; PRO-GIBB®; REGULEX®; RELEASE®; RELAX®; RYZUP®; STIMULATE®; VIGOR®
Biochem/physiol Actions
Phytohormone that controls important aspects of plant growth: germination, elongation, and flowering. The effects are mediated by inducing degradation of the DELLA repressor protein, and probably other minor signalling pathways.
Safety Profile
Mildly toxic by ingestion. Questionable carcinogen with experimental tumorigenic data. hlutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
It crystallises from EtOAc, EtOAc/pet ether, MeOH/pet ether or Me2CO/pet ether. [Cross J Chem Soc 3022 1960, Beilstein 18 III/IV 6533.]
Toxicity evaluation
75 ppm of Gibberellic acid (GA3) in drinking water was continuously administered orally to rats (Sprague-Dawley albino) ad libitum for 50 days. The lipid peroxidation end product MDA significantly increased in the lungs, heart, and kidney of rats treated with GA3 without significant change in the spleen. Antioxidant enzyme activities such as SOD significantly increased in the lungs and stomach and decreased in the spleen and heart tissues of rats treated with GA3[4].
References
[1]https://en.wikipedia.org/wiki/Gibberellic_acid
[2]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002599/
[3] Gupta, Ramwant, and S K Chakrabarty. “Gibberellic acid in plant: still a mystery unresolved.” Plant signaling & behavior vol. 8,9 (2013): e25504. doi:10.4161/psb.25504
[4]Celik, Ismail et al. “Evalution of toxicity of abcisic acid and gibberellic acid in rats: 50 days drinking water study.” Journal of enzyme inhibition and medicinal chemistry vol. 22,2 (2007): 219-26. doi:10.1080/14756360600988955
Gibberellic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao Trust Agri Chemical Co.,Ltd | +8613573296305 | aroma@qdtrustagri.com | China | 165 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales05@airuikechemical.com | China | 994 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
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View Lastest Price from Gibberellic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-16 | Gibberellic acid
77-06-5
|
US $290.00-250.00 / kilograms | 1kilograms | 90% | 100tons | Hebei Dangtong Import and export Co LTD | |
 |
2024-04-22 | Gibberellins
77-06-5
|
US $1.00 / KG | 1KG | 99.91% | 200000 | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-04-19 | Gibberellic acid
77-06-5
|
US $650.00 / g | 1g | 98 | 500 Kg | R&D Scientific Inc. |
-
- Gibberellic acid
77-06-5
- US $290.00-250.00 / kilograms
- 90%
- Hebei Dangtong Import and export Co LTD
-
- Gibberellins
77-06-5
- US $1.00 / KG
- 99.91%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- Gibberellic acid
77-06-5
- US $650.00 / g
- 98
- R&D Scientific Inc.
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