Capromab Pendetide
- CAS No.
- 145464-28-4
- Chemical Name:
- Capromab Pendetide
- Synonyms
- Prostascint;Cytogen 356;Capromab Pendetide;Oncoscint prostate;Research Grade Capromab (DHG01303);Immunoglobulin G 1 (mouse monoclonal 7E11-C5.3 anti-human prostatic carcinoma cell), disulfide with mouse monoclonal 7E11-C5.3 light chain, dimer, N(sup 6)-(N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl)-N(sup 2)-(N-glycyl-L-tyrosyl)-L-lysine conjugate
- CBNumber:
- CB11379720
- Molecular Formula:
- C10H15N5O11P2
- Molecular Weight:
- 443.200522
- MDL Number:
- MOL File:
- 145464-28-4.mol
| NCI Dictionary of Cancer Terms | capromab pendetide; ProstaScint |
|---|---|
| FDA UNII | BDO5072GRX |
Capromab Pendetide Chemical Properties,Uses,Production
Uses
Monoclonal antibody.
General Description
Capromab (ProstaScint Kit for the preparation of In-111capromab pendetide, murine) is an MAb (murine IgG1 κ)that derives from an initial sensitization with a glycoproteinexpressed by prostate epithelium known as prostate surfacemembrane antigen (PSMA). The MAb recognizes PSMAspecifically and thus is specific for prostate adenocarcinomas.The drug is used in newly diagnosed patients withproven prostate cancer who are at high risk for pelvic lymphmetastasis. PSMA has been found in many primary andmetastatic prostate cancer lesions. The cytoplasmic domainmarker 7E11-C5.3 reacts with more than 95% of adenocarcinomasevaluated.
To join the indium-111 to the antibody, a linker-chelatoris used. This moiety is glycyltyrosyl-(N-ethylenetriaminepentaaceticacid)-lysine HCl.
Capromab Pendetide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 | amber@biochempartner.com | China | 3063 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10055 | 58 |
| AntibodySystem | 027-65279366 18162686757 | biolab-reagents@atagenix.com | China | 9819 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 13720134139 | orders@jknbiochem.com | China | 5278 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 0731-18670069958 18670069958 | 184792226@qq.com | China | 3060 | 58 |
| Olix (Shanghai) Pharmaceutical Technology Co., Ltd | 17316404525 | 209533805@qq.com | China | 9621 | 58 |