10Panx
- CAS No.
- 955091-53-9
- Chemical Name:
- 10Panx
- Synonyms
- 10Panx;Trp Arg Gln Ala Ala Phe Val Asp Ser Tyr;L-Tyrosine, L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-
- CBNumber:
- CB12522406
- Molecular Formula:
- C58H79N15O16
- Molecular Weight:
- 1242.36
- MDL Number:
- MFCD09842372
- MOL File:
- 955091-53-9.mol
- MSDS File:
- SDS
10Panx price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2152 | 10Panx1 trifluoroacetate salt ≥98% (HPLC) | 955091-53-9 | 1MG | $147 | 2024-03-01 | Buy |
| TRC | T895400 | L-Tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosineTFASalt | 955091-53-9 | 1mg | $50 | 2021-12-16 | Buy |
| TRC | T895400 | L-Tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosineTFASalt | 955091-53-9 | 25mg | $305 | 2021-12-16 | Buy |
| Usbiological | 254341 | 10Panx | 955091-53-9 | 1mg | $389 | 2021-12-16 | Buy |
| ApexBio Technology | A2700 | 10Panx | 955091-53-9 | 25mg | $400 | 2021-12-16 | Buy |
10Panx Chemical Properties,Uses,Production
Uses
L-Tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosine is a connexin mimetic peptide that inhibits pannexin-1 gap junctions.
Biological Activity
10panx is a mimetic inhibitory peptide of panx1, which is a mammalian protein ectopically expressed to function as a hemi-channel, that readily and reversibly inhibits the panx1 currents. 10panx has attracted increasing attention as it allows scientists readily and reliably to examine inhibition of panx1 in cells where efficient and consistent delivery of sirna is highly difficult. according to results of multiple previous studies, 10panx selectively inhibits p2x7r-induced dye uptake without altering other aspects of r2x7r activation and atp-evoked membrane currents, constitutive dye-uptake and hemichannel-like currents that are induced by the overexpression of panx1, and atp-mediated il-1β release.pablo pelegrin and annmarie surprenant. pannexin-1 mediates large pore formation and interleukin-1β release by the atp-gated p2x7 receptor. the embo journal (2006) 25, 5071-5082
storage
Store at -20°C
10Panx Preparation Products And Raw materials
Raw materials
Preparation Products
10Panx Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 18951903616; | info@adooq.cn | China | 2989 | 60 |
| Creative Peptides | info@creative-peptides.com | United States | 6084 | 56 |