LaniceMine
- CAS No.
- 153322-05-5
- Chemical Name:
- LaniceMine
- Synonyms
- LaniceMine;(1S)-1-phenyl-2-pyridin-2-ylethanamine;2-PyridineethanaMine, a-phenyl-, (aS)-;2-Pyridineethanamine, α-phenyl-, (αS)-;(S)-1-phenyl-2-(pyridin-2-yl)ethanamine;(1S)-1-PHENYL-2-(PYRIDIN-2-YL)ETHAN-1-AMINE
- CBNumber:
- CB12611425
- Molecular Formula:
- C13H14N2
- Molecular Weight:
- 198.27
- MDL Number:
- MFCD00924222
- MOL File:
- 153322-05-5.mol
Boiling point | 307.7±27.0 °C(Predicted) |
---|---|
Density | 1.097±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | ≤20mg/ml in ethanol;30mg/ml in DMSO;5mg/ml in dimethyl formamide |
form | neat oil |
pka | 8.29±0.10(Predicted) |
FDA UNII | 9TMU325RK3 |
LaniceMine price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 9002129 | Lanicemine ≥95% | 153322-05-5 | 5mg | $50 | 2024-03-01 | Buy |
Cayman Chemical | 9002129 | Lanicemine ≥95% | 153322-05-5 | 10mg | $95 | 2024-03-01 | Buy |
Cayman Chemical | 9002129 | Lanicemine ≥95% | 153322-05-5 | 25mg | $176 | 2024-03-01 | Buy |
Cayman Chemical | 9002129 | Lanicemine ≥95% | 153322-05-5 | 50mg | $300 | 2024-03-01 | Buy |
TRC | L173950 | Lanicemine | 153322-05-5 | 5mg | $40 | 2021-12-16 | Buy |
LaniceMine Chemical Properties,Uses,Production
Description
Lanicemine is a non-
Uses
Lanicemine is a non-selective voltage-dependant NMDA channel blocker. It is a potential anti-depressant which does not cause psychotomimetic activity. Potential anti-hypertensive agent.
in vitro
previous study with lanicemine and ketamine found that both compounds could bind with low-to-moderate affinity to sites within the nmda channel pore, exhibit strong voltage dependence, and have similar lack of nr2a vs nr2b subunit selectivity [1].
in vivo
in animal study, cortical eeg recordings were obtained from rats trained to perform an auditory detection task for food reward. results showed that both lanicemine and ketamine produced pronounced dose-dependent elevations in spontaneous gamma-band eeg, but only gamma changes for ketamine were tightly coupled to increases in locomotor activity, indicating that lanicemine not only engaged brain circuits involved in the generation of gamma-eeg, but also influenced these networks independent of the broader systemslevel disruptions typical of ketamine [1].
IC 50
4-7 μm
References
[1] g. sanacora, m. a. smith, s. pathak, et al. lanicemine: a low-trapping nmda channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects. molecular psychiatry 19(9), 978-985 (2014).
LaniceMine Preparation Products And Raw materials
Raw materials
Preparation Products
LaniceMine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6011 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Xi'an ZB Biotech Co.,Ltd | +8618591943808 | sales01@xazbbio.com | China | 816 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
ATK CHEMICAL COMPANY LIMITED | 3429815786 13301662590 | sales@atkchemical.com | China | 10004 | 55 |
Changzhou Xuanye Technology Co., Ltd | 15195022192 | 279776773@qq.com | China | 2010 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
Shanghai Dexuan Pharmaceutical Technology Co., Ltd | 1701086315 | dexuanpharma@126.com | China | 9478 | 58 |
View Lastest Price from LaniceMine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-09-05 | Lanicemine
153322-05-5
|
US $50.00 / kg | 1kg | 0.99 | 20tons | Hebei Yanxi Chemical Co., Ltd. |
- Lanicemine
153322-05-5
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.