MLS-0315848 hydrochloride
- CAS No.
- 1135318-57-8
- Chemical Name:
- MLS-0315848 hydrochloride
- Synonyms
- ML095;ML095 HCL;MLS-0315848 hcl;ML095 hydrochloride;MLS-0315848 hydrochloride;CID-25067483 hydrochloride;1-(3,4-dihydroxyphenyl)-2-(2-ethylimidazol-1-yl)ethanone;1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride;1-(3,4-Dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-Ethanone hydrochloride;CID-25067483,ML-095,ML 095,ML095 hydrochloride,ML095,inhibit,ML 095 hydrochloride,CID25067483,Inhibitor,CID 25067483
- CBNumber:
- CB12750702
- Molecular Formula:
- C13H15ClN2O3
- Molecular Weight:
- 282.72
- MDL Number:
- MFCD25563261
- MOL File:
- 1135318-57-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
MLS-0315848 hydrochloride price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15173 | ML-095 (hydrochloride) ≥98% | 1135318-57-8 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 15173 | ML-095 (hydrochloride) ≥98% | 1135318-57-8 | 5mg | $118 | 2024-03-01 | Buy |
| Cayman Chemical | 15173 | ML-095 (hydrochloride) ≥98% | 1135318-57-8 | 10mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 15173 | ML-095 (hydrochloride) ≥98% | 1135318-57-8 | 25mg | $374 | 2024-03-01 | Buy |
| TRC | D454515 | 1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanoneHydrochloride | 1135318-57-8 | 1mg | $50 | 2021-12-16 | Buy |
MLS-0315848 hydrochloride Chemical Properties,Uses,Production
Uses
1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride is a biochemical inhibitor of placental alkaline phosphatase (PLAP) and is used to elucidate the key biological functions and natural substrates of human PLAP.
Biological Activity
ml-095 (hydrochloride) is a specific plap inhibitor [1].alkaline phosphatases are hydrolase enzymes responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. there are three isozymes of alkaline phosphatases: placental alkaline phosphatase (plap), intestinal alkaline phosphatase (iap), and tissue non-specific alkaline phosphatase (tnap). placental alkaline phosphatase (plap) is highly expressed in primate placental tissue and the biological function is still unknown. however, plap-like enzymes are detected in serum of patients with primary testicular tumors, in particular seminoma and other cancers [1].ml-095 (cid-25067483) is a biochemical inhibitor of plap and will be useful to elucidate the key biological functions and natural substrates of human plap. ml095 is a specific plap inhibitor and inhibited plap, tnap and iap with ic50 values of 2.1, >100 and 53 μm, respectively. ml095 exhibited greater than 25-fold selectivity over tissue non-specific alkaline phosphatase (tnap) and intestinal alkaline phosphatase (iap) [1].
References
[1]. lanier m, cashman j, sergienko e, et al. placental alkaline phosphatase (plap) luminescent hts assay - probe 2.
MLS-0315848 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
MLS-0315848 hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4182 | 55 | |
| Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 | huahero21@sina.com | China | 361 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2985 | 58 |