ANTI-LAMIN A/C
- CAS No.
- Chemical Name:
- ANTI-LAMIN A/C
- Synonyms
- Anti-FPL;Anti-IDC;Anti-LFP;ANTI-LAMA;ANTI-LMNA;ANTI-LMN1;Anti-LNMI;Anti-CDDC;Anti-EMD2;Anti-FPLD
- CBNumber:
- CB1318078
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01633588
- MOL File:
- Mol file
ANTI-LAMIN A/C price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4200236 | Monoclonal Anti-Lamin A/C antibody produced in mouse clone 4C11, purified from hybridoma cell culture | 25μL | $169 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4501255 | Anti-LAMA1 antibody produced in rabbit affinity isolated antibody | 100μG | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4200236 | Monoclonal Anti-Lamin A/C antibody produced in mouse clone 4C11, purified from hybridoma cell culture | 200μL | $571 | 2024-03-01 | Buy | |
| Sigma-Aldrich | L1293 | Anti-Lamin A (C-terminal) antibody produced in rabbit ~1?mg/mL, affinity isolated antibody, buffered aqueous solution | 200μL | $555 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | ATB0014741 | ANTI-LAMIN A/C 95.00% | 5MG | $498.03 | 2021-12-16 | Buy |
ANTI-LAMIN A/C Chemical Properties,Uses,Production
Uses
Anti-Lamin A (C-terminal) antibody is suitable for use in western blot (0.1-0.2 μg/mL) using HeLa nuclear extract. This antibody can also be used in indirect immunofluorescence (1-2 μg/mL) using HeLa cells, rat NRK and mouse 3T3 cells. Additionally, anti-Lamin A (C-terminal) antibodies are suitable for use in immunoblotting (approx. 70 kDa). Cleaved fragments of lamin A may form additional bands at 45-50 kDa.
Uses
Mouse monoclonal clone 4C11 anti-Lamin A/C antibody is used to tag lamins A and/or C for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. It is used as a probe to determine the presence and roles of lamins A and/or C in nuclear envelope structure and function. This antibody may be used in several immunochemical techniques including immunoblotting (~72/63 kDa), immunoprecipitation and immunofluorescence.
General Description
Lamin is a structural protein of the nuclear lamina. Lamin A is a type A lamin encoded by the LMNA gene. Lamin A contains 664 amino acids and is expressed in most somatic cells. It contains α-helical rod domain to enable assembly into filaments, a nuclear localization sequence, and a carboxy-terminal CAAX box isoprenylation sequence for nuclear membrane targeting.
Biochem/physiol Actions
Lamin A cut into a 47kDa fragment that facilitates chromatin condensation and nuclear degradation during cell death
ANTI-LAMIN A/C Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-LAMIN A/C Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai guandao biology engineering co., ltd | 18818239863 18818239863 | 3171921642@qq.com | China | 8884 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Shanghai guandao biology engineering co., ltd | 58 |