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ARS-1630

CAS No.
1698055-86-5
Chemical Name:
ARS-1630
Synonyms
CPD2016;ARS-1630;ARS-1630;ARS 1630;ARS1630;inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630;(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
CBNumber:
CB13386449
Molecular Formula:
C21H17ClF2N4O2
Molecular Weight:
430.84
MDL Number:
MOL File:
1698055-86-5.mol
Last updated:2023-05-21 10:59:17

ARS-1630 Properties

Boiling point 614.7±55.0 °C(Predicted)
Density 1.434±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 69 mg/mL (160.15 mM)
pka 6.03±0.35(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

ARS-1630 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0035117 ARS-1630 98.01% 1698055-86-5 5mg $250 2021-12-16 Buy
ChemScene CS-0035117 ARS-1630 98.01% 1698055-86-5 10mg $350 2021-12-16 Buy
ChemScene CS-0035117 ARS-1630 98.01% 1698055-86-5 25mg $690 2021-12-16 Buy
ChemScene CS-0035117 ARS-1630 98.01% 1698055-86-5 50mg $990 2021-12-16 Buy
ChemScene CS-0035117 ARS-1630 98.01% 1698055-86-5 100mg $1300 2021-12-16 Buy
Product number Packaging Price Buy
CS-0035117 5mg $250 Buy
CS-0035117 10mg $350 Buy
CS-0035117 25mg $690 Buy
CS-0035117 50mg $990 Buy
CS-0035117 100mg $1300 Buy

ARS-1630 Chemical Properties,Uses,Production

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1630 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
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BOC Sciences
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Neostar United (Changzhou) Industrial Co., Ltd.
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TargetMol Chemicals Inc.
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Career Henan Chemica Co
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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InvivoChem
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Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3421 58
ARS-1630 CPD2016 ARS-1630;ARS 1630;ARS1630 (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one 2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]- inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630 1698055-86-5