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2,6-Dichloropurine

2,6-Dichloropurine structure

CAS No.: 5451-40-1

Chemical Name:: 2,6-Dichloropurine

Synonyms: 2,6-DICHLORO-9H-PURINE;2,6-dichloro-7H-purine;2,6-dichloro-1H-purine;NSC 18395;Dichloropurine;6-Dichloropurine;2,6-DICHLOROPURINE;2,6-Dichloropurine>Cefepime Intermediate;2,6-Dichloropurine.97%

CBNumber:: CB1720642

Molecular Formula:: C5H2Cl2N4

Molecular Weight:: 189

MDL Number:: MFCD09749894

MOL File:: 5451-40-1.mol

MSDS File:: SDS

Last updated:2024-04-19 20:05:26

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2,6-Dichloropurine Properties

Melting point	185-195 °C (dec.) (lit.)
Boiling point	310.62°C (rough estimate)
Density	1.7265 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble
pka	5.22±0.20(Predicted)
form	Crystalline Powder
color	White to yellow
Water Solubility	soluble
BRN	9354
InChIKey	RMFWVOLULURGJI-UHFFFAOYSA-N
CAS DataBase Reference	5451-40-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

P264-P270-P301+P310-P405-P501

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-22

Safety Statements

22-24/25-37/39-26-36

RIDADR

UN2811

WGK Germany

HazardClass

IRRITANT

HS Code

29349990

NFPA 704

	1
3		0

2,6-Dichloropurine price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D73103	2,6-Dichloropurine 97%	5451-40-1	1g	$17.48	2024-03-01	Buy
Sigma-Aldrich	D73103	2,6-Dichloropurine 97%	5451-40-1	5g	$83.2	2024-03-01	Buy
TCI Chemical	D2470	2,6-Dichloropurine >97.0%(HPLC)(T)	5451-40-1	1g	$24	2024-03-01	Buy
TCI Chemical	D2470	2,6-Dichloropurine >97.0%(HPLC)(T)	5451-40-1	5g	$60	2024-03-01	Buy
Alfa Aesar	B21289	2,6-Dichloropurine, 97%	5451-40-1	1g	$76.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
D73103	1g	$17.48	Buy
D73103	5g	$83.2	Buy
D2470	1g	$24	Buy
D2470	5g	$60	Buy
B21289	1g	$76.65	Buy

2,6-Dichloropurine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

2,6-Dichloropurine is used in the synthesis of 2,6-diamino-substituted purine derivatives as potential cardiomyogenesis inducing agents.

Uses

Suzuki-Miyaura cross-coupling between halopurines and arylboronic acids in water-acetonitrile.1

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 404, 1958 DOI: 10.1021/ja01535a040

Purification Methods

It can be recrystallised from 150 parts of boiling H2O and dried at 100o to constant weight. It is soluble in EtOAc. The HgCl2 salt separates from EtOH solution. UV: max 275nm ( 8.9K) at pH 1; and 280nm ( 8.5K) at pH 11 [Elion & Hitchings J Am Chem Soc 78 3508 1956, Schaeffer & Thomas J Am Chem Soc 80 3738 1958, Beaman & Robins J Appl Chem (London) 12 432 1962, Montgomery J Am Chem Soc 78 1928 1956]. [Beilstein 26 III/IV 1747.]

2,6-Dichloropurine synthesis

Synthesis of 2,6-Dichloropurine from 6-Chloroguanine

2,6-Dichloropurine Preparation Products And Raw materials

Raw materials

HYPOXANTHINE-1-OXIDE ADENINE N(1)-OXIDE MONOHYDRATE, 98 1,5-Dihydropyrrolo[3,2-a]pyrimidine-2,4-dion Isoamyl nitrite Xanthine

6-Chloroguanine Guanine

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Preparation Products

Cladribine 2,6-Dichloro-7-methylpurine 7H-Purine, 2,6-dichloro-7-(1-methylethyl)- 2,6-dichloro-9-(1-methylethyl)-9H-purine 9H-Purine, 2,6-dichloro-9-propyl-

2,6-Dichloropurine Suppliers

Global( 567)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Ribio Biotech Co.,Ltd	010-62664360 +8613328773880	wucy@ribio.com.cn	China	117	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12471	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	sales@zhswyy.com	China	242	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	18232	58
airuikechemical co., ltd.	+undefined86-15315557071	sales05@airuikechemical.com	China	994	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	3001	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55

Supplier	Advantage
Beijing Ribio Biotech Co.,Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 2,6-Dichloropurine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-16	2,6-Dichloropurine 5451-40-1	US $455.00-440.00 / kg	10kg	99%	100Tons	Hebei Dangtong Import and export Co LTD
2024-05-11	2,6-Dichloropurine 5451-40-1	US $0.00-0.00 / kg	0.10000000149011612kg	99	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.
2024-04-20	2,6-Dichloropurine 5451-40-1	US $1.00 / KG	1KG	99.91%	200000	Ouhuang Engineering Materials (Hubei) Co., Ltd

2,6-Dichloropurine
5451-40-1
US $455.00-440.00 / kg
99%
Hebei Dangtong Import and export Co LTD

2,6-Dichloropurine
5451-40-1
US $0.00-0.00 / kg
99
Chongqing Zhihe Biopharmaceutical Co., Ltd.

2,6-Dichloropurine
5451-40-1
US $1.00 / KG
99.91%
Ouhuang Engineering Materials (Hubei) Co., Ltd

2,6-Dichloropurine Spectrum

2,6-Dichloropurine(5451-40-1)MS 2,6-Dichloropurine(5451-40-1)¹HNMR 2,6-Dichloropurine(5451-40-1)¹³CNMR 2,6-Dichloropurine(5451-40-1)IR1 2,6-Dichloropurine(5451-40-1)IR2

5451-40-1(2,6-Dichloropurine)Related Search:

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2,6-DICHLORO-9-(2-DEOXY-3,5,DI-O-(4-METHYLBENZOYL-BETA-D-ERYTHROPENTOFURANOSYL)-9H-PURINE) 2,6-DICHLORO-9-METHYL-9H-PURINE 2,6,8-TRICHLORO-7-METHYLPURINE

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2,6-DICHLOROPURINE 2,6-Dichloropurine.97% 1H-Purine, 2,6-dichloro- Dichloropurine Cefepime Intermediate 9H-Purine, 2,6-dichloro- 6-Dichloropurine NSC 18395 2,6-Dichloropurine> 2,6-Dichloropurine USP/EP/BP 2,6-DICHLORO-9H-PURINE 2,6-dichloro-1H-purine 2,6-dichloro-7H-purine 5451-40-1 2001-2-5 5451-41-0 C5H2ClN4 HETERO CHLORIDE Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Purines Building Blocks Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Intermediates & Fine Chemicals Pharmaceuticals Nucleotides Fused Ring Systems Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks PurinesHeterocyclic Building Blocks Biochemistry Nucleobases and their analogs Nucleosides, Nucleotides & Related Reagents Nucleic acids Bases & Related Reagents Pyridines, Pyrimidines, Purines and Pteredines Halides Purine Nucleotides and Nucleosides Purines FINE Chemical & INTERMEDIATES Starting Raw Materials & Intermediates Heterocycles 5451-40-1