ChemicalBook >> CAS DataBase List >>Cyclosporin C
Cyclosporin C
- CAS No.
- 59787-61-0
- Chemical Name:
- Cyclosporin C
- Synonyms
- CL246;WF-3484;CS-2545;CS-2546;CYCLOSPORIN C;Thr2-cyclosporine;Cyclosporin C, >=95%;Cyclosporine IMpurity-C;Cyclosporin Impurity C;Cyclosporine Impurity 3
- CBNumber:
- CB2153074
- Molecular Formula:
- C62H111N11O13
- Molecular Weight:
- 1218.61
- MDL Number:
- MFCD06410945
- MOL File:
- 59787-61-0.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 144-1460C |
|---|---|
| alpha | D20 -255° (c = 0.5 in chloroform); D20 -182° (c = 0.5 in methanol) |
| Boiling point | 1316.0±65.0 °C(Predicted) |
| Density | 1.033±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO: ≥10mg/mL |
| pka | 13.06±0.70(Predicted) |
| form | Colorless to off-white crystalline solid. |
| color | White to Off-White |
| InChIKey | JTOKYIBTLUQVQV-PCACHRFWSA-N |
| CAS DataBase Reference | 59787-61-0 |
| FDA UNII | 6S744L5508 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H362-H350-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Cyclosporin C price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29152 | Cyclosporin C | 59787-61-0 | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 29152 | Cyclosporin C | 59787-61-0 | 25mg | $330 | 2024-03-01 | Buy |
| Cayman Chemical | 29152 | Cyclosporin C | 59787-61-0 | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 29152 | Cyclosporin C | 59787-61-0 | 10mg | $183 | 2024-03-01 | Buy |
| TRC | C988905 | Cyclosporin C | 59787-61-0 | 5mg | $265 | 2021-12-16 | Buy |
Cyclosporin C Chemical Properties,Uses,Production
Description
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. It is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs = 0.1-5 μg/ml). Cyclosporin C (15 μg/ml) inhibits vaccinia virus replication in infected BSC40 cells by 98.82%. It inhibits lymphocyte proliferation induced by the mitogens concanavalin A (ConA; ), phytohemagglutinin L (PHA), and pokeweed mitogen (PWM), as well as proliferation induced by alloantigen in mixed lymphocyte culture when used at a concentration of 100 ng/ml. Cyclosporin C (100 ng/ml) inhibits the local graft versus host (GVH) reaction in mice receiving splenocyte grafts.
Chemical Properties
White Solid
Uses
A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Uses
Cyclosporin C is a minor analogue of the cyclosporin complex produced by a number of fungal species, including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin C possesses immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A.
storage
+4°C
Cyclosporin C Preparation Products And Raw materials
Global( 190)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from Cyclosporin C manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-26 | Cyclosporin C
59787-61-0
|
US $0.00-0.00 / g | 1g | 95% | 1kg | Jiangsu Nata Opto-electronic Material Co.,Ltd. | |
 |
2022-02-25 | Thr2-Cyclosporine
59787-61-0
|
US $299.00 / KG | 1KG | 99% | 1 ton | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | Thr2-Cyclosporine | US $16.00 / KG | 1KG | 99% | 2kgs | Hong Kong Tiansheng New Material Trading Co., Ltd |
-
- Cyclosporin C
59787-61-0
- US $0.00-0.00 / g
- 95%
- Jiangsu Nata Opto-electronic Material Co.,Ltd.
-
- Thr2-Cyclosporine
59787-61-0
- US $299.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- Thr2-Cyclosporine
- US $16.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
59787-61-0(Cyclosporin C)Related Search:
CYCLOSPORIN C
Thr2-cyclosporine
Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Thr-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
WF-3484
7-L-Threoninecyclosporin A
Cyclosporine IMpurity-C
7-L-Threoninecyclosporin A, WF 3484
7-Threonine-cyclosporin A
Cyclosporin C, >=95%
Cyclosporine C/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
30-(1-hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriaconta
CS-2545
CS-2546
cyclo-[MeBmt-Thr-Sar-MeLeu-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal]
Cyclosporine EP Impurity C
CL246
Cyclosporin Impurity C
Cyclosporin Impurity 3(Cyclosporin C)
Cyclosporin A, 7-L-threonine-
Cyclosporine Impurity 3
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-Hydroxy-2-methylhex-4-en-1-yl)-30-((R)-1-hydroxyethyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
(3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,1
(3R,6S,9S,12R,15R,18S,21R,24S,30R,33S)-30-(1-Hydroxyethyl)-33-(1-hydroxy-2-methylhex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Cyclosporin C, EvoPure?
59787-61-0
69787-61-0
59767-61-0
C62H111N11O13
Intermediates & Fine Chemicals
Peptides
Pharmaceuticals
ACTIVE PHARMACEUTICAL INGREDIENTS