ChemicalBook >> CAS DataBase List >>Polyinosinic-polycytidylic acid sodium salt
Polyinosinic-polycytidylic acid sodium salt
- CAS No.
- 42424-50-0
- Chemical Name:
- Polyinosinic-polycytidylic acid sodium salt
- Synonyms
- Poly (I:C) Na;Poly(I:C) sodium;POLY I POLY C, NA;Polymyocyte sodium salt;POLY[I] POLY[C] SODIUM SALT;polyinosinic-polycytidylic acid sodium;polyI-polyC sodium salt compound solution;POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT;Polyinosinicacid-polycytidylicacidsodiumsal;POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
- CBNumber:
- CB2187556
- Molecular Formula:
- C19H27N7O16P2
- Molecular Weight:
- 671.41
- MDL Number:
- MFCD00131957
- MOL File:
- 42424-50-0.mol
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | TR0175000 |
Polyinosinic-polycytidylic acid sodium salt price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P0913 | Polyinosinic–polycytidylic acid sodium salt ≥99% (less than 1% free nucleotides, TLC) | 42424-50-0 | 10mg | $134 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0913 | Polyinosinic–polycytidylic acid sodium salt ≥99% (less than 1% free nucleotides, TLC) | 42424-50-0 | 50mg | $457 | 2024-03-01 | Buy |
| Sigma-Aldrich | 528906 | Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded - CAS 42424-50-0 - Calbiochem Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. | 42424-50-0 | 10MG | $115 | 2024-03-01 | Buy |
| Sigma-Aldrich | P1530 | Polyinosinic–polycytidylic acid sodium salt TLR ligand tested | 42424-50-0 | 25mg | $210 | 2024-03-01 | Buy |
| Sigma-Aldrich | P1530 | Polyinosinic–polycytidylic acid sodium salt TLR ligand tested | 42424-50-0 | 100mg | $627 | 2024-03-01 | Buy |
Polyinosinic-polycytidylic acid sodium salt Chemical Properties,Uses,Production
Uses
Polyinosinic Acid & Polycytidylic Acid Sodium Salt (double-stranded) is a TLR3 (Toll-like receptor 3) agonist.
Uses
TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Biological Activity
Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.
storage
Store at -20°C
Polyinosinic-polycytidylic acid sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 112)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Weitai Biological Pharmaceutical Co.,Ltd. | +8613282012786 | sales@weitai-pharmaceutical.com | China | 61 | 58 |
| HangZhou RunYan Pharma Technology Co.,LTD. | +86-88660901 +86-18112526015 | sales@runyanpharma.com | China | 326 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15954 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21688 | 55 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27843 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5999 | 58 |
View Lastest Price from Polyinosinic-polycytidylic acid sodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-03-13 | Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na;
42424-50-0
|
US $0.00 / kg | 1kg | 90.0%Min. HPLC | 1000kg | HangZhou RunYan Pharma Technology Co.,LTD. | |
 |
2021-12-08 | Polyi polycytidylic acid sodium salt(Poly I:C) (PIC)
42424-50-0
|
US $0.00-0.00 / KG | 10g | ≥90% | 2tons | Hangzhou Weitai Biological Pharmaceutical Co.,Ltd. | |
 |
2021-11-02 | POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT
42424-50-0
|
US $5079.00 / Kg/Bag | 1KG | 50% | 2T | Baoji Guokang Healthchem co.,ltd |
-
- Polyinosinic–polycytidylic acid sodium salt ; Poly (I: C); Poly (I:C) Na;
42424-50-0
- US $0.00 / kg
- 90.0%Min. HPLC
- HangZhou RunYan Pharma Technology Co.,LTD.
-
- Polyi polycytidylic acid sodium salt(Poly I:C) (PIC)
42424-50-0
- US $0.00-0.00 / KG
- ≥90%
- Hangzhou Weitai Biological Pharmaceutical Co.,Ltd.
-
- POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT
42424-50-0
- US $5079.00 / Kg/Bag
- 50%
- Baoji Guokang Healthchem co.,ltd
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42424-50-0
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