ChemicalBook >> CAS DataBase List >>Methyl 2,3-dichloropropionate
Methyl 2,3-dichloropropionate
- CAS No.
- 3674-09-7
- Chemical Name:
- Methyl 2,3-dichloropropionate
- Synonyms
- 2,3-dichloropropionate;METHYL-A,B-DICHLOROPROPIONATE;METHYL 2,3-DICHLOROPROPIONATE;Methyl 2,3-dichloropropanoate;Methyl2,3-Dichloropropionate>Methyl 2,3-dichloropropionate,98%;METHYL ALPHA,BETA-DICHLOROPROPIONATE;2,3-dichloro-propanoicacimethylester;2,3-DICHLOROPROPIONIC ACID METHYL ESTER;Methyl 2,3-dichloropropionate,70%,tech.
- CBNumber:
- CB2257329
- Molecular Formula:
- C4H6Cl2O2
- Molecular Weight:
- 157
- MDL Number:
- MFCD00000944
- MOL File:
- 3674-09-7.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| Boiling point | 52-55 °C/2 mmHg (lit.) |
|---|---|
| Density | 1.325 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 145 °F |
| storage temp. | Store below +30°C. |
| solubility | Soluble in ether, acetone, ethanol. |
| color | Colorless to Almost colorless |
| BRN | 1701891 |
| InChI | InChI=1S/C4H6Cl2O2/c1-8-4(7)3(6)2-5/h3H,2H2,1H3 |
| InChIKey | OFHMODDLBXETIK-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C(Cl)CCl |
| CAS DataBase Reference | 3674-09-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanoic acid, 2,3-dichloro-, methyl ester(3674-09-7) |
| EPA Substance Registry System | Propanoic acid, 2,3-dichloro-, methyl ester (3674-09-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318-H227-H314-H341 | |||||||||
| Precautionary statements | P201-P202-P210-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P313-P403+P235-P405-P501-P210e-P260h-P303+P361+P353-P305+P351+P338-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-10 | |||||||||
| Safety Statements | 23-24/25-37/39-26-16 | |||||||||
| RIDADR | 1993 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| NFPA 704 |
|
Methyl 2,3-dichloropropionate price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.18319 | Methyl 2,3-dichloropropionate for synthesis | 3674-09-7 | 10ml | $44.2 | 2024-03-01 | Buy |
| TCI Chemical | D0408 | Methyl 2,3-Dichloropropionate >95.0%(GC) | 3674-09-7 | 10g | $26 | 2024-03-01 | Buy |
| Alfa Aesar | B21993 | Methyl 2,3-dichloropropionate, 98% | 3674-09-7 | 25g | $46.65 | 2024-03-01 | Buy |
| Alfa Aesar | B21993 | Methyl 2,3-dichloropropionate, 98% | 3674-09-7 | 100g | $102.65 | 2024-03-01 | Buy |
| Alfa Aesar | B21993 | Methyl 2,3-dichloropropionate, 98% | 3674-09-7 | 500g | $396.65 | 2024-03-01 | Buy |
Methyl 2,3-dichloropropionate Chemical Properties,Uses,Production
Chemical Properties
clear colorless to slightly yellow liquid
Uses
Methyl 2,3-dichloropropionate can be used to produce 2-chloro-acrylic acid methyl ester at Heating. It is used as pharmaceutical intermediate.
Application
Methyl 2,3-Dichloropropanoate is a useful reagent in preparation of oxidative fragmentation and coupling of catharanthine analogs to vindoline.
Synthesis
Preparation of Methyl 2,3-dichloropropanoate:
Methyl acrylate (2366 g, 27.5 mol) and dimethylformamide (DMF) (40 g, 0.55 mol) was placed in a 3-liter three necked flask fitted with a stirrer, thermometer, inlet tube and gas trap. Chlorine (950 g, 0.48 mol) was passed into the methyl acrylate rapidly over a period of ten hours while the temperature was kept below 40°C. Reaction progress was monitored by gas chromatography (GC). When it seemed that 50 percent of chlorine was consumed, the reaction was stopped. The reaction mass was taken for distillation to separate methylacrylate and Methyl 2,3-dichloropropanoate. The contents were subjected to vacuum distillation. Methyl 2,3-dichloropropanoate was collected distilling at 70°C with 15mm.Yield (%):77.2, Purity (%) = 98.
Methyl 2,3-dichloropropionate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 156)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 18232 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15956 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| AB PharmaTech,LLC | 323-480-4688 | United States | 989 | 55 | |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from Methyl 2,3-dichloropropionate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-02 | Methyl 2,3-dichloropropanoate
3674-09-7
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-02-16 | Methyl 2,3-dichloropropionate
3674-09-7
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2021-04-21 | Methyl 2,3-dichloropropionate
3674-09-7
|
US $100.00 / g | 1000g | 98% | 10tons | Puyang Huicheng Electronic Materials Co., Ltd. |
-
- Methyl 2,3-dichloropropanoate
3674-09-7
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- Methyl 2,3-dichloropropionate
3674-09-7
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- Methyl 2,3-dichloropropionate
3674-09-7
- US $100.00 / g
- 98%
- Puyang Huicheng Electronic Materials Co., Ltd.
3674-09-7(Methyl 2,3-dichloropropionate)Related Search:
METHYL 2,3-DICHLOROPROPIONATE
METHYL-A,B-DICHLOROPROPIONATE
METHYL ALPHA,BETA-DICHLOROPROPIONATE
2,3-DICHLOROPROPIONIC ACID METHYL ESTER
2,3-dichloro-propanoicacimethylester
Methyl 2,3-dichloropropanoate
Propionic acid, 2,3-dichloro-, methyl ester
METHYL-2,3-DICHLOROPROPIONATE, 1000MG, N EAT
Methyl 2,3-dichloropropionate, tech., 70%
Propanoic acid, 2,3-dichloro-, methyl ester
2,3-dichloro-propanoic acid methyl ester
Methyl 2,3-dichloropropionate,98%
Methyl 2,3-dichloropropionate,70%,tech.
Methyl 2,3-dichloropropionate, tech., 70% 25ML
METHYL 2,3-DICHLOROPROPIONATE FOR SYNTHE
Methyl2,3-Dichloropropionate>
2,3-dichloropropionate
Propanoic acid, 2,3-dichloro-, methyl ester (9CI, ACI)
2,3-dichloro-Propanoic acid methyl ester (9CI ACI)
3674-09-7
648-19-2
674-09-7
3674-09-07
ClCH2CHClCOOCH3
Alpha Sort
M
MAlphabetic
META - METH
Volatiles/ Semivolatiles