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HEMOCYANIN, KEYHOLE LIMPET

CAS No.
9013-72-3
Chemical Name:
HEMOCYANIN, KEYHOLE LIMPET
Synonyms
KLH;HEMOCYANIN;haemocyanin;HeMocyanins;blue carrier;HEMOCYANIN-HG;Keyhole limpet;BLUE CARRIER(R);HEMOCYANIN TYPE VIII;KLH, BES/Mg2+ Buffer
CBNumber:
CB2327970
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00131280
MOL File:
Mol file
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

HEMOCYANIN, KEYHOLE LIMPET Properties

storage temp. 2-8°C
solubility H2O: soluble
form PBS solution
NCI Dictionary of Cancer Terms keyhole limpet hemocyanin; KLH
NCI Drug Dictionary keyhole limpet hemocyanin

SAFETY

Risk and Safety Statements

Risk Statements  52/53
Safety Statements  23-24/25-61
WGK Germany  1
10-21

HEMOCYANIN, KEYHOLE LIMPET price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 374817 Hemocyanin, Keyhole Limpet, Megathura crenulata, Glycerol Hemocyanin, Keyhole Limpet, Megathura crenulata, Glycerol, is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies. 9013-72-3 1g $1710 2024-03-01 Buy
Sigma-Aldrich 374805 Hemocyanin, Keyhole Limpet, 9013-72-3 250mg $311 2023-06-20 Buy
Sigma-Aldrich 374805 Hemocyanin, Keyhole Limpet, Megathura crenulata Hemocyanin, Keyhole Limpet, Megathura crenulata, CAS 9013-72-3, is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies. 9013-72-3 1g $1010 2023-06-20 Buy
Sigma-Aldrich H8283 Hemocyanin from Megathura crenulata (keyhole limpet) PBS solution 9013-72-3 50mg $154 2024-03-01 Buy
Sigma-Aldrich H8283 Hemocyanin from Megathura crenulata (keyhole limpet) PBS solution 9013-72-3 100mg $261 2024-03-01 Buy
Product number Packaging Price Buy
374817 1g $1710 Buy
374805 250mg $311 Buy
374805 1g $1010 Buy
H8283 50mg $154 Buy
H8283 100mg $261 Buy

HEMOCYANIN, KEYHOLE LIMPET Chemical Properties,Uses,Production

Uses

Hemocyanin from Limulus polyphemus hemolymph has been used:

  • in electrophoretic field gradient focusing as a reference standard for optimizing fluorescence quenching for noncolored proteins
  • as standard protein for pH based crystallization screening experiments
  • in peptide conjugation studies

Uses

Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response.
Hemocyanin was used to study if antipeptide antibodies specifically recognize the l1 protein of the human papilloma virus of type 31. It was also used to study the acid-induced unfolding of didecameric keyhole limpet hemocyanin.

General Description

Gastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.

Biochem/physiol Actions

The largest hemocyanin molecules consisting of 48 (8 × 6) subunits are present in horseshoe crabs (Limulus polyphemus) have up to eight distinct subunits type (6 × subunit type I, 8 × II, 2 × IIA, 8 × IIIA, 8 × IIIB, 8 × IV, 4 × V, 4 × VI).

HEMOCYANIN, KEYHOLE LIMPET Preparation Products And Raw materials

Raw materials

Preparation Products

HEMOCYANIN, KEYHOLE LIMPET Suppliers

Global( 77)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Ipure Biology Co., Ltd
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Career Henan Chemica Co
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Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15885 55
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