DENDROTOXIN-K
- CAS No.
- Chemical Name:
- DENDROTOXIN-K
- Synonyms
- DENDROTOXIN-K
- CBNumber:
- CB2411934
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01866187
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
DENDROTOXIN-K price More Price(1)
DENDROTOXIN-K Chemical Properties,Uses,Production
Uses
Dendrotoxin-K is suitable for use as a potassium voltage-gated channel subfamily A member 1 (Kv1.1) channel blocker in axon and human embryonic kidney (HEK293) cells. It has also been used as a selective blocker of Kv channels in mice.
Biochem/physiol Actions
Dendrotoxin-K (DTXk) is isolated from mamba snake Dendroaspis polylepis and interacts with the β-turn region in the N-terminal sequence of the potassium channel. It inhibits tumor progression in gefitinib-resistant non-small cell lung cancer cells. DTXk induces neuronal damage in the hippocampus via N-methyl-d-aspartate (NMDA) and non-NMDA receptors.
DENDROTOXIN-K Preparation Products And Raw materials
Raw materials
Preparation Products
DENDROTOXIN-K Suppliers
Global( 10)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
(DENDROTOXIN-K)Related Search:
DENDROTOXIN-K
Voltage-gated Ion Channels
Ion Channels
Potassium Channel Modulators
Monovalent Ion Channels
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Monovalent Ion Channels
Potassium Channel Modulators
Voltage-gated Ion Channels