Cloquintocet-mexyl
- CAS No.
- 99607-70-2
- Chemical Name:
- Cloquintocet-mexyl
- Synonyms
- Cloquintocet-1;oquintocet-MexyL;cloquitocet_mexyl;CLOQUINTOCET-MEXYL;Cloquintocet-methyl;Adagrasib Impurity 59;Cloquintocet-mexyl >Cloquintocet-mexyl Standard;99607-70-2 (CLOQUINTOCET-MEXYL);high quality Cloquintocet-mexyl
- CBNumber:
- CB3243431
- Molecular Formula:
- C18H22ClNO3
- Molecular Weight:
- 335.83
- MDL Number:
- MFCD01632329
- MOL File:
- 99607-70-2.mol
| Melting point | 69° |
|---|---|
| Boiling point | 448.4±30.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| vapor pressure | 0-54.4Pa at 25-185.9℃ |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| pka | 1.94±0.29(Predicted) |
| color | White to Off-White |
| Merck | 14,2401 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| LogP | 5.2-5.24 at 25℃ and pH5-9.1 |
| Surface tension | 56.8-57.2mN/m at 590μg/L and 20℃ |
| Dissociation constant | 3.55 at 20℃ |
| CAS DataBase Reference | 99607-70-2(CAS DataBase Reference) |
| FDA UNII | 99W15EH2M3 |
| Pesticides Freedom of Information Act (FOIA) | Cloquintocet mexyl |
| EPA Substance Registry System | Cloquintocet-mexyl (99607-70-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H410 |
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| RIDADR | UN 3077 |
| WGK Germany | 2 |
| RTECS | AG1265000 |
| HS Code | 2933.49.3000 |
| Toxicity | LD50 in rats (mg/kg): >2000 orally; >2000 dermally; LC50 (4 hr) in rats: >935 mg/m3 by inhalation (Amrein) |
Cloquintocet-mexyl price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 31678 | Cloquintocet-mexyl PESTANAL | 99607-70-2 | 250mg | $91.1 | 2024-03-01 | Buy |
| TCI Chemical | C2682 | Cloquintocet-mexyl >98.0%(HPLC)(T) | 99607-70-2 | 1g | $48 | 2024-03-01 | Buy |
| TRC | C583525 | Cloquintocet-mexyl | 99607-70-2 | 2.5g | $120 | 2021-12-16 | Buy |
| Matrix Scientific | 171095 | 1-Methylhexyl 2-[(5-chloro-8-quinolinyl)oxy]acetate | 99607-70-2 | 1g | $148 | 2021-12-16 | Buy |
| Chem-Impex | 39361 | Cloquintocet-mexyl,≥98%(Assaybytitration,HPLC) ≥98%(Assaybytitration,HPLC) | 99607-70-2 | 1G | $154.92 | 2021-12-16 | Buy |
Cloquintocet-mexyl Chemical Properties,Uses,Production
Description
Cloquintocet-mexyl is a colourless crystalline herbicide safener. It is categorized as Class III toxin.
Chemical Properties
beige solid
Uses
Cloquintocet-mexyl is used as a herbicide.
Uses
Cloquintocet-mexyl is a herbicide. It is used to control coarse annual grass of the family poaceae (gramineae). lt was developed by the swiss ciba geigy in the 1980s and the patent has expired.
Definition
ChEBI: Heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate is a member of the class of quinolines that is quinoline which is substituted by a chloro group at position 5 and by a 2-[(heptan-2-yl)oxy]-2-oxoethoxy group at position 8. It is an aromatic ether, an organochlorine compound, a member of quinolines and a carboxylic ester.
Agricultural Uses
Cloquintocet-mexyl is a safener that can be used in conjunction with various herbicides to reduce phytotoxicity to crops. Though effective as a safener, the manufacture, storage, and use of cloquintocet-mexyl containing products can present challenges owing to its sensitivity to water and its low melting temperature (i.e., 61-69° C. for technical material). When products containing cloquintocet-mexyl are prepared, stored, or used in the presence of water, cloquin tocet-mexyl can undergo hydrolysis to form cloquintocet acid, and/or form a needle-shaped, crystalline hydrate that can, lead to clogged spray nozzles during spray applications and/or possibly increased levels of crop phytotoxicity.
Carcinogenicity
In accordance with the EPA Proposed EPA Weight-of-the-Evidence Categories, August 1999, the HIARC classified cloquintocet-mexyl as "not likely to be a human carcinogen." Carcinogenicity studies in rats and mice did not show increased incidence of spontaneous tumor formation. With negative mutagenic test battery, it is suggested that cloquintocet-mexyl (CGA 185072) is not likely to be a human carcinogen.
Metabolism
Metabolism studies in rats indicated that approximately 40% of the administered dose of cloquintocet-mexyl was absorbed through the gastrointestinal tract and subsequently excreted via the urine. Fecal excretion accounted for approximately 60% of the administered dose. The chemical was rapidly eliminated (more than 80% of the administered dose) via feces and urine within 48 hours post-dosing. Sex, dosing regime, and dose levels had little effect on the excretion pattern. Excretion patterns were similar between the biliary cannulated and non-cannulated animals indicating that there was no enterohepatic circulation of the chemical. Three days after administration, tissue radioactivity accounted for less than 0.3% of the administered dose (or was non-detectable) and was not detectable in the expired air. At day three post-dosing, most tissue residues of radioactivity were below the limit of detection. The major metabolic pathway of cloquintocet-mexyl was ester hydrolysis to yield 5-chloro-8-quinolinoxy acetic acid, the major metabolite in the fecal and urinary pools.
Toxicity evaluation
Cloquintocet-mexyl has a low order of acute oral, dermal, and inhalation toxicity. It is slightly irritating to the eyes and non-irritating to the skin. Cloquintocet-mexyl is a skin sensitizer. The chemical is not genotoxic and is not a reproductive and developmental toxicant. There is no evidence of neurotoxicity in the available studies. Cloquintocet-mexyl is classified as “not likely to be a human carcinogen.” The main metabolite for cloquintocet-mexyl is 5-chloro-8-quin-linoxyacetic acid, and testing on the metabolite is part of the toxicology database for cloquintocet-mexyl.
Cloquintocet-mexyl Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6000 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 952 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
View Lastest Price from Cloquintocet-mexyl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-14 | Cloquintocet-mexyl
99607-70-2
|
US $30.00 / g | 1g | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2023-11-22 | Cloquintocet-mexyl
99607-70-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-06 | Cloquintocet-mexyl
99607-70-2
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Cloquintocet-mexyl
99607-70-2
- US $30.00 / g
- 98%
- hebei hongtan Biotechnology Co., Ltd
-
- Cloquintocet-mexyl
99607-70-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Cloquintocet-mexyl
99607-70-2
- US $30.00-10.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
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