ChemicalBook >> CAS DataBase List >>Alverine citrate
Alverine citrate
- CAS No.
- 5560-59-8
- Chemical Name:
- Alverine citrate
- Synonyms
- GaMatran;CalMabel;Spacolin;SpasMona;NSC 35459;Profenine;Prophelan;Proverine;AntispasMin;SpasMaverine
- CBNumber:
- CB3303160
- Molecular Formula:
- C26H35NO7
- Molecular Weight:
- 473.57
- MDL Number:
- MFCD00035086
- MOL File:
- 5560-59-8.mol
Last updated:2024-03-21 18:02:16
| Melting point | 100-102° |
|---|---|
| storage temp. | 2-8°C |
| solubility | Slightly soluble in water and in methylene chloride, sparingly soluble in ethanol (96 per cent). |
| color | White to Off-White |
| InChIKey | RYHCACJBKCOBTJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 5560-59-8(CAS DataBase Reference) |
| FDA UNII | 9JFB58YK1E |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29214990 |
Alverine citrate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000687 | Alverine citrate salt European Pharmacopoeia (EP) Reference Standard | 5560-59-8 | y0000687 | $223 | 2024-03-01 | Buy |
| Sigma-Aldrich | A0424 | Alverine citrate salt | 5560-59-8 | 5g | $215.6 | 2024-03-01 | Buy |
| Cayman Chemical | 26892 | Alverine (citrate) | 5560-59-8 | 1g | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 26892 | Alverine (citrate) | 5560-59-8 | 5g | $63 | 2024-03-01 | Buy |
| TRC | A575780 | AlverineCitrate | 5560-59-8 | 10g | $65 | 2021-12-16 | Buy |
Alverine citrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Originator
Alverine citrate,Kemikos
Uses
anticholinergic
Uses
An adrenergic-β3 receptor agonist. Antispasmodic.
Uses
Used for studies of pharmacological activity including:
- Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
- Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
- Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
- Drug effects viewed from a signal transduction network perspective
- Enhanced cytotoxic effect of proteasome inhibitor MG132
- Mechanism of action on phasic smooth muscles
Definition
ChEBI: The citrate salt of alverine, resulting from the reaction of equimolar amounts of alvarine and citric acid. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used in the treatment of irritable bowel syndrome.
Manufacturing Process
2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium
hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt
as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was
obtained.
In practice it is usually used as citrate.
Therapeutic Function
Anticholinergic, Spasmolytic
Alverine citrate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 183)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Joiny Pharmaceutical Co.,LTD | +8613681955282 | gyd@joiny-pharma.com | China | 228 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 2931 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from Alverine citrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-10 | Alverine citrate
5560-59-8
|
US $0.00 / kg | 1kg | 99.0~101.0% | 2000kg | Shanghai Joiny Pharmaceutical Co.,LTD | |
 |
2022-10-14 | Alverine citrate
5560-59-8
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2022-08-23 | Alverine citrate
5560-59-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- Alverine citrate
5560-59-8
- US $0.00 / kg
- 99.0~101.0%
- Shanghai Joiny Pharmaceutical Co.,LTD
-
- Alverine citrate
5560-59-8
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Alverine citrate
5560-59-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
5560-59-8(Alverine citrate)Related Search:
Alverine base or citrate
alverine dihydrogen citrate
Profenil citrate
AntispasMin
CalMabel
n-ethyl-3,3'-diphenyldipropylamine citrate
N-ETHYL-3,3'-DIPHENYLDIPROPYLAMINE CITRATE SALT
N-ETHYL-3,3-DIPHENYLDIPROPYLAMINE CITRATE SALT
GaMatran
N-Ethyl-N-(3-phenylpropyl)benzenepropanaMine 2-Hydroxy-1,2,3-
propanetricarboxylate
NSC 35459
Profenine
Prophelan
Proverine
Spacolin
SpasMaverine
SpasMona
Alverine citrate iMpurity
Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
Alverine Citrate Imp. (EP)
BIS-GAMMA-PHENYLPROPYLETHYLAMINE DIHYDROGEN CITRATE
ALVERINE CITRATE
ALVERINE CITRATE SALT
Alverine Citric Acid-D5
N-Ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine citrate
Alverine Citric Acid
Alverine citrate CRS
Alverine citrate ISO 9001：2015 REACH
Alverine Citrate (NSC 35459)
Alverine citrate EP9.0
N-Ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate
5560-59-8
C26H35NO7
C20H27NC6H8O7
Organic Building Blocks
Nitrogen Compounds
Building Blocks
Amine Salts
Pharmaceutical intermediates
SPASMAVERINE
Amines
Aromatics
Intermediates & Fine Chemicals
Pharmaceuticals