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LAT-NET

LAT-NET Structure
LAT-NET structure
CAS No.
607351-44-0
Chemical Name:
LAT-NET
Synonyms
LAT-NET;LATANOPROST ETHYL AMIDE;Bimatoprost Impurity 20;13,14-Dihydro Bimatoprost;N-ETHYL-9ALPHA, 11ALPHA, 15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR PROST 5Z-EN-1-AMIDE;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethylhept-5-enamide;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-, (5Z)-
CBNumber:
CB3344563
Molecular Formula:
C25H39NO4
Molecular Weight:
417.58
MDL Number:
MFCD03412001
MOL File:
Mol file
Last updated:2023-06-08 09:03:09
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LAT-NET Properties

Boiling point 640.9±55.0 °C(Predicted)
Density 1.095±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 200 μg/ml
pka 14.84±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319-H336
Precautionary statements  P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
2 0

LAT-NET price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16822 Latanoprost ethyl amide ≥98% 607351-44-0 1mg $73 2024-03-01 Buy
Cayman Chemical 16822 Latanoprost ethyl amide ≥98% 607351-44-0 5mg $324 2024-03-01 Buy
Cayman Chemical 16822 Latanoprost ethyl amide ≥98% 607351-44-0 10mg $575 2024-03-01 Buy
TRC D450468 13,14-DihydroBimatoprost 607351-44-0 1mg $155 2021-12-16 Buy
AK Scientific 6557CR Latanoprostethylamide 607351-44-0 10mg $737 2021-12-16 Buy
Product number Packaging Price Buy
16822 1mg $73 Buy
16822 5mg $324 Buy
16822 10mg $575 Buy
D450468 1mg $155 Buy
6557CR 10mg $737 Buy

LAT-NET Chemical Properties,Uses,Production

Description

Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.

Uses

13,14-Dihydro Bimatoprost can be used as reactant/reagent for preparation of nitrooxy prostamides for treatment of glaucoma. Analog or impurity of the drug Bimatoprost (B386800).

Definition

ChEBI: Latanoprost ethyl amide is a prostanoid.

LAT-NET Preparation Products And Raw materials

Raw materials

Preparation Products

LAT-NET Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TopScience Biochemical 		00852-68527855 info@itopbiochem.com China Hong Kong 902 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Shenzhen Roark Pharma-Tec Co., Ltd. 13128912434 2880126944@qq.com China 2579 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Hubei Aiputi Bioengineering Co., Ltd. 17762444226 d17762444226@163.com China 2402 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Shanghai Zerui Biotechnology Co., Ltd. 021-54580889 18321124657 731997554@qq.com China 10614 58
Supplier Advantage
TopScience Biochemical 		58
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
Jinan blalong chemical co. LTD 58
Shenzhen Roark Pharma-Tec Co., Ltd. 58
TargetMol Chemicals Inc. 58
Hubei Aiputi Bioengineering Co., Ltd. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai Zerui Biotechnology Co., Ltd. 58

607351-44-0(LAT-NET)Related Search:

(Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER (-)-Corey Lactone Diol (5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromide 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA Dimethyl (2-oxo-4-phenylbutyl)phosphonate
17- Phenyl Trinor Prostaglandin F2α Methyl Amide CHEMPACIFIC 59929 HYDRIDE-L 15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA Bimatoprost Impurity 9
Bimatoprost Impurity 17 Bimatoprost Impurity 15 Bimatoprost Impurity 22 Bimatoprost Impurity 13 Bimatoprost Impurity 2 (Mixture of Diastereomers)
Bimatoprost Impurity 14 Bimatoprost Impurity 21 Bimatoprost Impurity 18

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LATANOPROST ETHYL AMIDE LAT-NET N-ETHYL-9ALPHA, 11ALPHA, 15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR PROST 5Z-EN-1-AMIDE Bimatoprost Impurity 20 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethylhept-5-enamide 13,14-Dihydro Bimatoprost 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-, (5Z)- 607351-44-0 C25H39NO4