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β-N-AcetylglucosaMinidase

CAS No.
9012-33-3
Chemical Name:
β-N-AcetylglucosaMinidase
Synonyms
NAG;MPS3B;NAGLU;MPS-IIIB;EC 3.2.1.52;EC 3.2.1.30;β-N-acetylhexosaminidase;β-N-AcetylglucosaMinidase;β-N-AcetylglucosaMinidase;Acetylglucosaminidase, B2
CBNumber:
CB3451584
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00081402
MOL File:
Mol file
Last updated:2023-05-04 15:16:06

β-N-AcetylglucosaMinidase Properties

Density 1.37[at 20℃]
vapor pressure 0.004Pa at 25℃
storage temp. 2-8°C
form lyophilized powder
Water Solubility 125g/L at 25℃
LogP -1.3 at 20℃

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501
Hazard Codes  B
Risk Statements  20/22-24-37/38-41-42
Safety Statements  53-26-36/37/39-45
WGK Germany  3
10

β-N-AcetylglucosaMinidase price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A2264 β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) ammonium sulfate suspension, ≥10?units/mg protein 9012-33-3 5units $165 2024-03-01 Buy
Sigma-Aldrich A2264 β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) ammonium sulfate suspension, ≥10?units/mg protein 9012-33-3 10units $302 2024-03-01 Buy
Sigma-Aldrich A6805 β-N-Acetylglucosaminidase from Streptococcus pneumoniae recombinant, expressed in E. coli, buffered aqueous solution 9012-33-3 1vial $639 2024-03-01 Buy
Sigma-Aldrich A2264 β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) ammonium sulfate suspension, ≥10?units/mg protein 9012-33-3 25units $566 2024-03-01 Buy
Sigma-Aldrich 110116 β1-2,3,4,6-N-Acetylglucosaminidase, 9012-33-3 1u $523 2024-03-01 Buy
Product number Packaging Price Buy
A2264 5units $165 Buy
A2264 10units $302 Buy
A6805 1vial $639 Buy
A2264 25units $566 Buy
110116 1u $523 Buy

β-N-AcetylglucosaMinidase Chemical Properties,Uses,Production

Uses

β -N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease 1 . Acetylglucosaminidase from Canavalia ensiformis has been used to study enzymic detachment of biofilms.

Uses

Bovine kidney β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer′s Disease .

Flammability and Explosibility

Not classified

Biochem/physiol Actions

β-N-Acetylglucosaminidase from Streptococcus pneumoniae is an extracellular glycosidase and has broad specificity over the β1-3 and β1-6 linkages present in mucins. It belongs to the glycoside hydrolase family 85 (GH85). Also called endo-β-N-acetylglucosaminidase, it cleaves at the asparagine residue of the di-N-acetylchitobiose structure in oligosaccharides and acts on fucosylated N-glycan core. Its deglycosylation functionality is exploited in studying functions of glycoproteins.

Purification Methods

Purify it by chromatography on DEAD-Biogel, hydroxylapatite chromatography and gel filtration through Sephacryl S200. Two isoforms: a hexosaminidase EI with Km 177WM

β-N-AcetylglucosaMinidase Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Shanghai Yingxin Laboratory Equipment Co., Ltd. 021-021-59178156 17002132182 3146474380@qq.com China 11609 58
Shanghai Baoman Biotechnology Co., Ltd. 021-62130998 baomanbio@163.com China 105 55
GlycoSciTech Co. Ltd, Jinan, China 18906399270 18906399270 watergreen77@yahoo.com China 157 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9823 79
Shanghai BeiZhuo Biotech Co., Ltd. 021-61119791,13386096464 bzswkf@foxmail.com China 3924 50
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15885 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
N-ACETYL-BETA-D-GLUCOSAMINIDASE N-ACETYL-BETA-D-GLYCOSAMINIDE-N-ACETYLGLUCOSAMINOHYDROLASE BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, STREPTOCOCCUS PNEUMONIAE BETA-N-ACETYLGLUCOSAMINIDASE BETA-N-ACETYLGLUCOSAMINIDASE H BETA-N-ACETYLHEXOSAMINIDASE EC 3.2.1.30 EC 3.2.1.52 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSIDE ACETAMIDODEOXYGLUCOHYDROLASE NAG Acetylglucosaminidase, beta- B-N-ACETYLGLUCOSAMINIDASE FROMASPERGILLU S NIGER B-N-ACETYLGLUCOSAMINIDASE AFROM HUMAN PL ACENTA B-N-ACETYLGLUCOSAMINIDASE, RECOMBINANT, EXPRESSED I B-N-ACETYLGLUCOSAMINIDASE P B-N-ACETYLGLUCOSAMINIDASEFROM HUMAN PLAC ENTA B-N-ACETYLGLUCOSAMINIDASE FROM JACK BEANS B-N-ACETYLGLUCOSAMINIDASE FROM BOVINEKID NEY B-N-ACETYLGLUCOSAMINIDASE AFROM PORCINE PLACENTA Acetylhexosaminidase, .beta.- β-n-acetylglucosaminidase from bovine kidney β-n-acetylglucosaminidase from canavalia ensiformis (jack bean) β-n-acetylglucosaminidase from human placenta β-n-acetylglucosaminidase from streptococcus pneumoniae BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, S. PNEUMONIAE, RECOMBINANT 2-Acetamido-2-deoxy-β-D-glucoside acetamidodeoxyglucohydrolase β-N-AcetylglucosaminidaseA from bovine epididymis β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase β-N-AcetylglucosaminidaseB from bovine epididymis β-N-Acetylglucosaminidase preparation from Aspergillus niger β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean),β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase, β-N-Acetylhexosaminidase Achromopeptidase Lysobacter sp. β-N-Acetylglucosaminidase A preparation from porcine placenta β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution β-N-Acetylglucosaminidase P preparation from human placenta β-N-Acetylglucosaminidase A preparation from human placenta MPS3B MPS-IIIB NAGLU β-N-AcetylglucosaMinidase β1-2,3,4,6-N-Acetylglucosaminidase, BETA-N-ACETYLGLUCOSAMINIDASE,JACK BEANS, ~50 U/MG, 500 UG* β1-2,3,4,6-N-Acetylglucosaminidase, Streptococcus pneumoniae, Recombinant, E. coli Hexosaminidase 3C from Saccharophagus degradans, Recombinant Hexosaminidase 3A from Thermotoga neapolitana, Recombinant Native Canavalia ensiformis β-N-Acetylglucosaminidase Native Human β-N-Acetylglucosaminidase Native Bovine β-N-Acetylglucosaminidase β-N-Acetylglucosaminidase from Streptococcus pneumoniae, Recombinant β-N-Acetylhexosaminidase from Streptococcus pyogenes, Recombinant beta-N-Acetylglucosaminidase from Streptococcus pneumoniae beta-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) beta-N-Acetylglucosaminidase from bovine kidney β-N-acetylhexosaminidase Acetylglucosaminidase, B2 β-N-AcetylglucosaMinidase