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TINZAPARIN SODIUM

CAS No.
12656-11-0
Chemical Name:
TINZAPARIN SODIUM
Synonyms
TINZAPARIN SODIUM
CBNumber:
CB3588026
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

TINZAPARIN SODIUM Properties

solubility Dissolve 1.0 g in 10 mL of water R. The solution is clear (2.2.1) and not more intensely coloured than intensity 5 of the range of reference solutions of the most appropriate colour (2.2.2, Method II)
NCI Dictionary of Cancer Terms tinzaparin sodium
FDA UNII 3S182ET3UA
NCI Drug Dictionary tinzaparin sodium

Pharmacokinetic data

Protein binding 14%
Excreted unchanged in urine 80-90%
Volume of distribution 3.1-5 Litres
Biological half-life 1.5 / 5.2 (detectable anti-Factor Xa activity persists for 24 hours)

TINZAPARIN SODIUM Chemical Properties,Uses,Production

Uses

Innohep (Pharmion).

Clinical Use


Peri- and postoperative surgical thromboprophylaxis
Treatment of DVT and pulmonary embolism
Prevention of thrombus formation in extracorporeal circulation during HD

Drug interactions

Potentially hazardous interactions with other drugs
Analgesics: increased risk of bleeding with NSAIDs - avoid concomitant use with IV diclofenac; increased risk of haemorrhage with ketorolac - avoid concomitant use.
Nitrates: anticoagulant effect reduced by infusions of glyceryl trinitrate.
Use with care in patients receiving oral anticoagulants, platelet aggregation inhibitors, aspirin or dextran.

Metabolism

Low molecular weight heparins are partially metabolised by desulphation and depolymerisation. The kidneys are the major site of tinzaparin excretion (approximately 70
% based on animal studies).

TINZAPARIN SODIUM Preparation Products And Raw materials

Raw materials

Preparation Products

TINZAPARIN SODIUM Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
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Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810 sales@sunlidabio.com China 3750 55
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Wuhan Yanzhe Technology Co., Ltd 15527250409 wenhaotian12@163.com China 4576 58
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TINZAPARIN SODIUM 12656-11-0