Pyrroloquinoline quinone disodium salt
- CAS No.
- 122628-50-6
- Chemical Name:
- Pyrroloquinoline quinone disodium salt
- Synonyms
- PQQ;PQQ Disodium Salt;pyrroloquinoline quineone;METHOXATIN DISODIUM SALT;disodium pyrroloquinolinedione tricarboxylate;disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylat;PYRROLOQUINOLINE QUINONE DISODIUM SALTPYRROLOQUINOLINE QUINONE DISODIUM SALT;PQQ-2Na;PQQ disodium;Methoxatin Disodium
- CBNumber:
- CB3728738
- Molecular Formula:
- C14H4N2Na2O8
- Molecular Weight:
- 374.17
- MDL Number:
- MFCD00151711
- MOL File:
- 122628-50-6.mol
| storage temp. | 2-8°C |
|---|---|
| Water Solubility | Water : 6.16 mg/mL (16.46 mM) |
| InChI | InChI=1S/C14H6N2O8.Na.H/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);; |
| InChIKey | UFVBOGYDCJNLPM-UHFFFAOYSA-L |
| SMILES | C(C1C=C(C(=O)O)N=C2C(=O)C(=O)C3C=C(C(=O)O)NC=3C=12)(=O)O.[NaH] |
| FDA UNII | 8WX58ADB2E |
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| RTECS | UY9454762 |
| F | 10-21 |
Pyrroloquinoline quinone disodium salt price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 80198 | Methoxatin disodium salt ≥97.0% (HPLC) | 122628-50-6 | 10mg | $276 | 2024-03-01 | Buy |
| Sigma-Aldrich | 80198 | Methoxatin disodium salt ≥97.0% (HPLC) | 122628-50-6 | 50mg | $1130 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | CHM0156690 | METHOXATIN DISODIUM SALT 95.00% | 122628-50-6 | 50MG | $1250.35 | 2021-12-16 | Buy |
| Chem-Impex | 42112 | Methoxatindisodiumsalt,≥97%(HPLC) ≥97%(HPLC) | 122628-50-6 | 10MG | $231.8 | 2021-12-16 | Buy |
| ChemScene | CS-5599 | Pyrroloquinolinequinonedisodiumsalt >98.0% | 122628-50-6 | 50mg | $560 | 2021-12-16 | Buy |
Pyrroloquinoline quinone disodium salt Chemical Properties,Uses,Production
Description
Pyrroloquinoline quinone disodium salt is a water-soluble quinone compound that has a strong antioxidant capacity. This product is a reddish-brown colored powder. It is isolated from cultures of methylotrophic bacteria and tissues of mammals. This essential nutrient is vital for mammals, playing a crucial role in enhancing immune function.
Uses
Pyrroloquinoline quinone disodium salt can act as an antioxidant and there is strong evidence that PQQ may play an important role in important pathways of cell signaling. PQQ plays a variety of physiological roles, such as promoting growth and reproduction and providing neurological and cardiovascular protection.
Application
Pyrroloquinoline quinone disodium salt protects cells from oxidative damage and increases the mitochondrial membrane potential, which is essential for the production of ATP. It also stimulates enzyme activities, such as glutathione peroxidase and glutathione reductase, and prevents lipid peroxidation of human serum. This compound also inhibits radiation-induced cellular damage by preventing DNA strand breakage. It may be effective in treating diseases related to oxidative stress, such as diabetes and cancer.
benefits
1.Antioxidant. PQQ (pyrroloquinoline quinone) is an antioxidant and based on research, it shows to be more powerful at fighting free radicals than vitamin C. Antioxidants work better together, so it is unclear if taking PQQ alone as a supplement can help stop any diseases.
2.Mitochondrial dysfunction. Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. One study tested PQQ supplements in men who did aerobic exercise for 6 weeks. It increased mitochondria by affecting certain proteins during exercise. Another study showed that dietary PQQ raised mitochondria activity.
3.Anti-diabetes. Problems with mitochondria are part of what causes diabetes. Animal data shows that PQQ supplements fix mitochondrial problems from diabetes and make diabetic mice respond better to insulin. Yet, there isn’t any evidence that PQQ can help people with diabetes.
4.Inflammation. PQQ might lower inflammation by lowering the C-reactive protein, interleukin-6, and other markers in your blood.
5.Nootropic. Substances that help memory, attention, and learning are sometimes called nootropics. Studies show that PQQ raises blood flow to the cerebral cortex. This supplement also may also memory problems in older people.
Sleep and mood. PQQ might help with better and longer sleep. By easing fatigue, it might also help to improve moods.
Source
Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.
Biochem/physiol Actions
In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.
Side effects
From Self-Hacked: Anecdotally, some people have reported mild headaches and insomnia – usually either if too much is taken or if someone is very sensitive to the effects of supplements.
From Dr. Axe: The most commonly reported pyrroloquinoline quinone side effects include headaches, drowsiness and fatigue. Extremely high doses can also be dangerous and have actually been associated with some serious and potentially life-threatening effects on health.
keep.health/pqq-pyrroloquinoline-quinone/
Pyrroloquinoline quinone disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Zelixir Biotech Co., Ltd. | +8618867646786 | neal.chen@zelixir.com | China | 230 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | sales006@ingredients-lonier.com | China | 2603 | 58 |
| Maintain Biotech Co., Ltd. | +86-75589664337 +86-15112661142 | cami@maintain-bio.com | China | 66 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3001 | 58 |
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 | guoyuan@eastchinapharm.com | China | 1615 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales05@airuikechemical.com | China | 994 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 | 2691956269@qq.com | China | 371 | 58 |
| Leading Chemical and Trading Co.,Ltd | +8615669938129 | sales@leadingchemical.com | China | 122 | 58 |
| ZhenYiBio Technology Inc | +8615309206328 | alexxue@zhenyibio.com | China | 299 | 58 |
Related articles
- Pyrroloquinoline quinone disodium salt: Benefits and Safety
- Pyrroloquinoline quinone disodium salt (PQQ) is a natural coenzyme in food that has highly efficient antioxidant activity and ....
- Apr 11，2024
Related Qustion
- Q:Is PQQ better than vitamin C or CoQ10?
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- Jan 24，2024
View Lastest Price from Pyrroloquinoline quinone disodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-15 | Pyrroloquinoline quinone disodium salt
122628-50-6
|
US $26.00 / box | 1box | 99% | 10000box | Shanghai Getian Industrial Co., LTD | |
 |
2024-05-15 | PQQ ( Pyrroloquinoline quinone)
122628-50-6
|
US $0.00 / G | 1G | 99% | 20 | CONTIDE BIOTECH CO.,LTD | |
 |
2024-05-15 | Pyrroloquinoline quinone disodium salt
122628-50-6
|
US $1.00-1.00 / kg | 1kg | 99% | 200KG | Jinan Million Pharmaceutical Co., Ltd |
-
- Pyrroloquinoline quinone disodium salt
122628-50-6
- US $26.00 / box
- 99%
- Shanghai Getian Industrial Co., LTD
-
- PQQ ( Pyrroloquinoline quinone)
122628-50-6
- US $0.00 / G
- 99%
- CONTIDE BIOTECH CO.,LTD
-
- Pyrroloquinoline quinone disodium salt
122628-50-6
- US $1.00-1.00 / kg
- 99%
- Jinan Million Pharmaceutical Co., Ltd
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