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INDEX NAME NOT YET ASSIGNED

CAS No.
2490676-19-0
Chemical Name:
INDEX NAME NOT YET ASSIGNED
Synonyms
FTX-6058 hydrochloride
CBNumber:
CB411029250
Molecular Formula:
C22H19ClFN5O2
Molecular Weight:
439.88
MDL Number:
MOL File:
2490676-19-0.mol
Last updated:2023-05-21 10:59:17

INDEX NAME NOT YET ASSIGNED Properties

storage temp. 4°C, away from moisture
solubility DMSO : 125 mg/mL (284.17 mM; ultrasonic and warming and heat to 60°C)

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Biological Activity

FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2]. FTX-6058 hydrochloride inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].

References

[1]. Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Supplier Advantage
Aladdin Scientific
58
FTX-6058 hydrochloride 2490676-19-0