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Saxagliptin hydrochloride

Saxagliptin hydrochloride structure

CAS No.: 709031-78-7

Chemical Name:: Saxagliptin hydrochloride

Synonyms: Saxaint-S;Saxagliptin HCL salt;Saxagliptin hydrochloride;(1S,3S,5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride;(1S,3S,5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile monohydrochloride;2-Azabicyclo[3.1.0]hexane-3-carbonitrile,2-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-,monohydrochloride, (1S,3S,5S)-

CBNumber:: CB42630096

Molecular Formula:: C18H25N3O2.HCl

Molecular Weight:: 351.88

MDL Number:: MFCD22572334

MOL File:: 709031-78-7.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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Saxagliptin hydrochloride Properties

Melting point	>219°C
storage temp.	-20°C
solubility	Soluble in DMSO (20 mg/ml)
form	solid
color	White
Stability	Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey	TUAZNHHHYVBVBR-PMEPUXBANA-N
SMILES	[C@@H](C12CC3CC(CC(C3)(O)C1)C2)(N)C(N1[C@@H](C[C@@H]2C[C@H]12)C#N)=O.Cl \|&1:0,15,17,19,r\|
FDA UNII	Z8J84YIX6L
NCI Drug Dictionary	saxagliptin hydrochloride

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H361-H335-H317-H351-H372
Precautionary statements	P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501

Saxagliptin hydrochloride price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	23697	Saxagliptin (hydrochloride) ≥98%	709031-78-7	5mg	$40	2024-03-01	Buy
Cayman Chemical	23697	Saxagliptin (hydrochloride) ≥98%	709031-78-7	10mg	$76	2024-03-01	Buy
Cayman Chemical	23697	Saxagliptin (hydrochloride)	709031-78-7	25mg	$148	2024-03-01	Buy
Cayman Chemical	23697	Saxagliptin (hydrochloride)	709031-78-7	50mg	$276	2024-03-01	Buy
Tocris	6507	Saxagliptinhydrochloride ≥98%(HPLC)	709031-78-7	50	$395	2021-12-16	Buy

Product number	Packaging	Price	Buy
23697	5mg	$40	Buy
23697	10mg	$76	Buy
23697	25mg	$148	Buy
23697	50mg	$276	Buy
6507	50	$395	Buy

Saxagliptin hydrochloride Chemical Properties,Uses,Production

Description

Saxagliptin (709031-78-7) is a clinically useful DPPIV inhibitor for the treatment of diabetes.1 ?Human DPP-IV Ki = 0.6 nM.2

Uses

Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

storage

Store at -20°C

References

Tahrani et al. (2009) Saxagliptin: a new DPP-4 inhibitor for the treatment of type 2 diabetes mellitus; Adv. Ther. 26 249 Augeri et al. (2005) Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes; J. Med. Chem. 48 5025

Saxagliptin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Saxagliptin hydrochloride Suppliers

Global( 113)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Beijing Yibai Biotechnology Co., Ltd	0086-182-6772-3597	sales04@yibaibiotech.com	CHINA	419	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8348	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Jiangxi Huihe Chemical Co., Ltd.	+86-19189228086 +8618858568638	wuzhouding@huihecrop.com	China	886	58
Hebei Duling International Trade Co. LTD	+8618712993135	sales01@hbduling.cn	China	15743	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Beijing Yibai Biotechnology Co., Ltd	58
career henan chemical co	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Alfa Chemistry	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Jiangxi Huihe Chemical Co., Ltd.	58
Hebei Duling International Trade Co. LTD	58

View Lastest Price from Saxagliptin hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-03-28	Saxagliptin hydrochloride 709031-78-7	US $50.00 / kg	1kg	99%	20 tons	Hebei Duling International Trade Co. LTD
	2020-01-14	Saxagliptin hydrochloride 709031-78-7	US $7.00 / KG	1KG	99%	1000kg	Career Henan Chemical Co

Saxagliptin hydrochloride
709031-78-7
US $50.00 / kg
99%
Hebei Duling International Trade Co. LTD

Saxagliptin hydrochloride
709031-78-7
US $7.00 / KG
99%
Career Henan Chemical Co

709031-78-7(Saxagliptin hydrochloride)Related Search:

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Saxagliptin hydrochloride (1S,3S,5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile monohydrochloride (1S,3S,5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride Saxagliptin HCL salt Saxaint-S 2-Azabicyclo[3.1.0]hexane-3-carbonitrile,2-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-,monohydrochloride, (1S,3S,5S)- 709031-78-7 C18H25N3O2HCl Saxagliptin Hydrochloride