ChemicalBook >> CAS DataBase List >>1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

CAS No.
241479-73-2
Chemical Name:
1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
Synonyms
1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-;1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methy...;1-[2-(2,5-Difluoro-phenyl)-3-methyl-oxiranylmethyl]-1H-[1,2,4]triazole;1H-1,2,4-Triazole,1-[[(2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiranyl]Methyl];1-[[(2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole;(2R,3S)-2-(2,5-DIFUOROPHENYL)-3-METHYL-((1H-1,2,4-TRIAZOL-1- YL)METHYL)OXIRANE;(2r,3s)-2-(2,5-difluorophenyl)-3-methyl-((1h-1,2,4-triazol-1-yl)methyl)oxirane;1-(((2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazol;1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole;(2R,3S)-2-(2,5-DIFUOROPHENYL)-3-METHYL-2-((1H-1,2,4-TRIAZOL-1- YL)METHYL)OXIRANE
CBNumber:
CB42707853
Molecular Formula:
C12H11F2N3O
Molecular Weight:
251.23
MDL Number:
MFCD30343823
MOL File:
241479-73-2.mol
MSDS File:
SDS
Last updated:2023-09-22 16:19:45

1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Properties

Boiling point 386.5±52.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
pka 2.75±0.10(Predicted)
InChI InChI=1S/C12H11F2N3O/c1-8-12(18-8,5-17-7-15-6-16-17)10-4-9(13)2-3-11(10)14/h2-4,6-8H,5H2,1H3/t8-,12+/m0/s1
InChIKey QYOWWJNQQPRWCO-QPUJVOFHSA-N
SMILES N1(C[C@]2(C3=CC(F)=CC=C3F)[C@H](C)O2)C=NC=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Chemical Properties,Uses,Production

Chemical Properties

1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole, also known as (2R,3S)-2-(2,5-Difluorophenyl)-3-methyl-[(1H-1,2,4-triazol-1-yl)methyl]oxirane, is a off white or white powder.

Preparation

(2R, 3R)-2-(2,5-Difluoro-phenyl)-1-[1 ,2,4]-triazol-1-yl-butane-2,3-diol (324 mg, 1.20 mmol) is dissolved in methylene chloride (13 ml) and then triethylamine (0.59 ml, 4.2.mmol) is added to the reaction mixture. The reaction mixture is cooled to 0 ℃ and methane sulfonyl chloride (0.21 ml, 2.72 mmol) dissolved in methylene chloride (4 ml) is added. After 4 hours, sodium hydroxide solution (0.98 ml) is added and the reaction mixture is stirred at room temperature overnight. Finally, 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole was obtained through purification.
1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-[[(2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole pictures 2024-05-21 1-[[(2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole
241479-73-2
US $0.00 / kg 1kg 98% 500kg Shanghai Joiny Pharmaceutical Co.,LTD
1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole pictures 2023-07-15 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
241479-73-2
US $0.00 / KG 0.1KG 98% 1000KGS Zhengzhou Anbu Chem Co.,Ltd
1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole pictures 2019-07-06 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
241479-73-2
US $100.00 / KG 1KG 98% 100KG Career Henan Chemical Co
1H-1,2,4-Triazole,1-[[(2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiranyl]Methyl] 1-[2-(2,5-Difluoro-phenyl)-3-methyl-oxiranylmethyl]-1H-[1,2,4]triazole (2r,3s)-2-(2,5-difluorophenyl)-3-methyl-((1h-1,2,4-triazol-1-yl)methyl)oxirane (2R,3S)-2-(2,5-difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)-methyl]-oxirane 1-[[(2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-triazole 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran-2-yl)Methy... (2R,3S)-2-(2,5-difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)-methyl]-oxirane (2R,3S)-2- 1H-1,2,4-Triazole, 1-[[(2R,3S)-2-(2,5-difluorophenyl)-3-methyl-2-oxiranyl]methyl]- (2R,3S)-2-(2,5-DIFUOROPHENYL)-3-METHYL-2-((1H-1,2,4-TRIAZOL-1- YL)METHYL)OXIRANE (2R,3S)-2-(2,5-DIFUOROPHENYL)-3-METHYL-((1H-1,2,4-TRIAZOL-1- YL)METHYL)OXIRANE 1-(((2R,3S)-2-(2,5-difluorophenyl)-3-Methyloxiran- 1-(((2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazol 241479-73-2 241479-73-4