4BP-TQS
- CAS No.
- 360791-49-7
- Chemical Name:
- 4BP-TQS
- Synonyms
- 4BP-TQS;4BP-TQS >=98% (HPLC);3H-Cyclopenta[c]quinoline-8-sulfonamide, 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-;4BP TQS,allosteric agonist,transmembrane site,Inhibitor,α7 nAChR,inhibit,Nicotinic acetylcholine receptors,4BPTQS,nAChR,4BP-TQS
- CBNumber:
- CB43067530
- Molecular Formula:
- C18H17BrN2O2S
- Molecular Weight:
- 405.31
- MDL Number:
- MOL File:
- 360791-49-7.mol
- MSDS File:
- SDS
4BP-TQS price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1167 | 4BP-TQS ≥98% (HPLC) | 360791-49-7 | 25mg | $359 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1167 | 4BP-TQS ≥98% (HPLC) | 360791-49-7 | 5mg | $102 | 2022-05-15 | Buy |
| Cayman Chemical | 21881 | 4BP-TQS | 360791-49-7 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21881 | 4BP-TQS | 360791-49-7 | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 21881 | 4BP-TQS | 360791-49-7 | 10mg | $184 | 2024-03-01 | Buy |
4BP-TQS Chemical Properties,Uses,Production
Uses
4BP-TQS is an agonist of human α7 nicotinic acetylcholine receptor (a7-nAChR), activates the channel via binding to an allosteric transmembrane site. Maximal activation of a7-nAChR by 4BP-TQS is eight fold greater than activation by a maximum dose of acetylcholine (Ach), and 4BP-TQS can poteniate an EC10 concentration of ACh to invoke a response that is 540-fold higher than the maximal dose of ACh alone.
Biochem/physiol Actions
4BP-TQS is an atypical agonist of a7-nAChR that binds to the receptor in an intrasubunit cavity, and activates the channel via a mechanism that is distinct from conventional agonists. Maximal activation of a7-nAChR by 4BP-TQS is eight fold greater than activation by a maximum dose of acetylcholine (Ach), and 4BP-TQS can poteniate an EC10 concentration of ACh to invoke a response that is 540-fold higher than the maximal dose of ACh alone.
4BP-TQS Preparation Products And Raw materials
Raw materials
Preparation Products
4BP-TQS Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4664 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4153 | 55 | |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |