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GC376

GC376 Structure
GC376 structure
CAS No.
1416992-39-6
Chemical Name:
GC376
Synonyms
376;GC376 sodium;GC376;GPC376;GC376 Sodium Bulk;GC376 (sodium salt);GC-376 sodium,GC376 sodium;3 alpha, 7 alpha-dyhydroxy-6-ethidene- cholanic acid;sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4- methylpentanamido)- 1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane- 1-;Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
CBNumber:
CB43333611
Molecular Formula:
C21H32N3NaO8S
Molecular Weight:
509.55
MDL Number:
MFCD31382192
MOL File:
1416992-39-6.mol
Last updated:2023-09-08 17:00:39
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GC376 Properties

storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMF: 10 mg/ml,DMSO: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
form A crystalline solid
FDA UNII H1NMJ5XDG5

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P304+P340
HS Code  2933299090

GC376 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth BG167367 GC 376 sodium 1416992-39-6 25mg $75 2021-12-16 Buy
Biosynth Carbosynth BG167367 GC 376 sodium 1416992-39-6 50mg $120 2021-12-16 Buy
Biosynth Carbosynth BG167367 GC 376 sodium 1416992-39-6 100mg $180 2021-12-16 Buy
Biosynth Carbosynth BG167367 GC 376 sodium 1416992-39-6 250mg $350 2021-12-16 Buy
Biosynth Carbosynth BG167367 GC 376 sodium 1416992-39-6 500mg $650 2021-12-16 Buy
Product number Packaging Price Buy
BG167367 25mg $75 Buy
BG167367 50mg $120 Buy
BG167367 100mg $180 Buy
BG167367 250mg $350 Buy
BG167367 500mg $650 Buy

GC376 Chemical Properties,Uses,Production

Description

GC376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.

Uses

GC 376 sodium is a potential small molecule inhibitor which may be able to reduce the viral load of SARS-CoV-2 3CLpro.

GC376 synthesis

1333231-44-9
1416992-39-6
Synthesis of GC376 from benzyl ((2S)-4-methyl-1-oxo-1-(((2S)-1-oxo-3-(2-oxo-1l2-pyrrolidin-3-yl)propan-2-yl)-l2-azanyl)pentan-2-yl)carbamate

GC376 Preparation Products And Raw materials

Raw materials

benzyl ((2S)-4-methyl-1-oxo-1-(((2S)-1-oxo-3-(2-oxo-1l2-pyrrolidin-3-yl)propan-2-yl)-l2-azanyl)pentan-2-yl)carbamate Methyl L-leucinate hydrochloride

Preparation Products

GC376 Suppliers

Global( 99)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Natural Micron Pharm Tech Co.,LTD
+86-18653895227 info@nmpharmtech.com China 94 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 994 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4022 58
Wuhan Nutra Biotechnology Co.,Ltd 		+8617786394783 nutrabiotech@outlook.com China 300 58
Henan Alfa Chemical Co., Ltd 		+8618339805032 alfa4@alfachem.cn China 13040 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Supplier Advantage
Shandong Natural Micron Pharm Tech Co.,LTD
58
Anhui Ruihan Technology Co., Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
career henan chemical co 		58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		58
Wuhan Nutra Biotechnology Co.,Ltd 		58
Henan Alfa Chemical Co., Ltd 		58
Nextpeptide Inc 		58
InvivoChem 		58

View Lastest Price from GC376 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GC376 pictures 2023-09-08 GC376
1416992-39-6
 US $30.00 / kg 1kg 99% 1000t/year Anhui Ruihan Technology Co., Ltd
GC376;GC-376 sodium pictures 2021-10-08 GC376;GC-376 sodium
1416992-39-6
 US $1.00-0.00 / g 1ASSAYS 98%+ 10kgs Wuhan Nutra Biotechnology Co.,Ltd
GC376 sodium pictures 2019-12-31 GC376 sodium
1416992-39-6
 US $6.60 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
  • GC376 pictures
  • GC376
    1416992-39-6
  • US $30.00 / kg
  • 99%
  • Anhui Ruihan Technology Co., Ltd
  • GC376 sodium pictures
  • GC376 sodium
    1416992-39-6
  • US $6.60 / KG
  • 97%-99%
  • Career Henan Chemical Co
GC376 GPC376 3 alpha, 7 alpha-dyhydroxy-6-ethidene- cholanic acid Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate (βS)-α-Hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid sodium salt 376 GC376 sodium GC376 (sodium salt) GC-376 sodium,GC376 sodium sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4- methylpentanamido)- 1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane- 1- GC376 Sodium Bulk 1416992-39-6 1416882-39-6