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ARS-1323

ARS-1323 Structure
ARS-1323 structure
CAS No.
1698024-73-5
Chemical Name:
ARS-1323
Synonyms
CPD2015;ARS-1323;ARS1323;ARS 1323;ARS-1323;Inhibitor,Ras,ARS1323,ARS 1323,inhibit,ARS-1323;2-Propen-1-one, 1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
CBNumber:
CB43369788
Molecular Formula:
C21H17ClF2N4O2
Molecular Weight:
430.84
MDL Number:
MOL File:
1698024-73-5.mol
Last updated:2023-09-04 15:51:00
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ARS-1323 Properties

Boiling point 614.7±55.0 °C(Predicted)
Density 1.434±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 125 mg/mL (290.13 mM)
pka 6.03±0.35(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

ARS-1323 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A778505 ARS-1620 1698024-73-5 2.5mg $1470 2021-12-16 Buy
ChemScene CS-0035015 ARS-1323 99.14% 1698024-73-5 5mg $220 2021-12-16 Buy
DC Chemicals DC10738 ARS-1323 >98% 1698024-73-5 10mg $350 2021-12-16 Buy
DC Chemicals DC10738 ARS-1323 >98% 1698024-73-5 50mg $800 2021-12-16 Buy
Product number Packaging Price Buy
A778505 2.5mg $1470 Buy
CS-0035015 5mg $220 Buy
DC10738 10mg $350 Buy
DC10738 50mg $800 Buy

ARS-1323 Chemical Properties,Uses,Production

Uses

ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1323 Preparation Products And Raw materials

Raw materials

Preparation Products

ARS-1323 Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3421 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58

ARS-1323 Spectrum

ARS-1323(1698024-73-5)1HNMR
ARS1323;ARS 1323;ARS-1323 ARS-1323 CPD2015 2-Propen-1-one, 1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]- Inhibitor,Ras,ARS1323,ARS 1323,inhibit,ARS-1323 1698024-73-5