Fentonium

CAS No.
5868-06-4
Chemical Name:
Fentonium
Synonyms
Z-326;FA-402;Ulcesium;Fentonium;Phentonium;Ketoscilium;[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide;[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide;3-hydroxy-2-phenyl-propionic acid [8-[2-keto-2-(4-phenylphenyl)ethyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide
CBNumber:
CB51178738
Molecular Formula:
C31H34BrNO4
Molecular Weight:
0
MDL Number:
MOL File:
5868-06-4.mol

Fentonium Properties

Melting point 203-205° (dec); mp 193-194°
alpha D23 -5.68° (c = 5 in DMF); D25 -4.7° (c = 5 in DMF)
FDA UNII 26BF4S8FO5
ATC code A03BB04

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice (mg/kg): 12.1 i.v.; >400 s.c. and orally (Teotino, Della Bella)

Fentonium Chemical Properties,Uses,Production

Originator

Hoelcesium,Zambon,Italy

Manufacturing Process

5.50g (0.02 mol) of p-phenylphenacyl bromide were dissolved in 56 cc of anhydrous acetone previously heated to about 40°C. This solution was added, with stirring, to a solution of 5.70 g (0.02 mol) of 1-hyoscyamine in 43 cc of anhydrous acetone; the reaction solution was maintained at 45°C and stirred for about six hours.
After standing overnight in the refrigerator, the precipitate was collected by filtration and dried in vacuo at 60°C. Yield: 10.2 g; MP = 193°C to 194°C.

Therapeutic Function

Anticholinergic, Spasmolytic

Fentonium Preparation Products And Raw materials

Raw materials

Preparation Products

Fentonium Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Supplier Advantage
TargetMol Chemicals Inc.
58
Fentonium FA-402 Ketoscilium Phentonium Ulcesium Z-326 [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide [8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide 3-hydroxy-2-phenyl-propionic acid [8-[2-keto-2-(4-phenylphenyl)ethyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide 5868-06-4 C31H34BrNO4