neogermbudine

CAS No.
595-64-2
Chemical Name:
neogermbudine
Synonyms
neogermbudine;4α,9-Epoxycevane-3β,4,7α,14,15α,16β,20-heptol 3-[(2S,3R)-2,3-dihydroxy-2-methylbutanoate]15-[(R)-2-methylbutanoate];Cevane-3,4,7,14,15,16,20-heptol, 4,9-epoxy-, 3-[(2S,3R)-2,3-dihydroxy-2-methylbutanoate] 15-[(2R)-2-methylbutanoate], (3β,4α,7α,15α,16β)-
CBNumber:
CB51386896
Molecular Formula:
C37H59NO12
Molecular Weight:
709.87
MDL Number:
MOL File:
595-64-2.mol

neogermbudine Properties

Melting point 149-152°C
Boiling point 827.8±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
pka 11.36±0.70(Predicted)

neogermbudine Chemical Properties,Uses,Production

Description

A hypotensive alkaloid present in Veratrum viride, this base is obtained as colourless crystals from C6H6 . It has [α]25D - 12° (c 1.0, pyridine) and belongs to the steroidal group of alkaloids. Acid hydrolysis furnishes germine, 2- methylbutyric acid and threo( - )-2: 3-dihydroxy-2-methylbutyric acid. The exact structure has not yet been determined.

References

Myersetal., f. Amer. Chern. Soc., 77,3348 (1955)

neogermbudine Preparation Products And Raw materials

Raw materials

Preparation Products

neogermbudine 4α,9-Epoxycevane-3β,4,7α,14,15α,16β,20-heptol 3-[(2S,3R)-2,3-dihydroxy-2-methylbutanoate]15-[(R)-2-methylbutanoate] Cevane-3,4,7,14,15,16,20-heptol, 4,9-epoxy-, 3-[(2S,3R)-2,3-dihydroxy-2-methylbutanoate] 15-[(2R)-2-methylbutanoate], (3β,4α,7α,15α,16β)- 595-64-2