ChemicalBook >> CAS DataBase List >>L-Homocystine

L-Homocystine

L-Homocystine structure

CAS No.: 626-72-2

Chemical Name:: L-Homocystine

Synonyms: (2S,2'S)-4,4'-Disulfanediylbis(2-aMinobutanoic acid);H-HoCys-OH;(H-HCY-OH)2;(H-Hcy-OH)?;H-L-HCystine;(H-HOCYS-OH)2;H-L-HOCYSTINE;(H-Hcys-OH) 2;L-Homocystine;(H-HOMOCYS-OH)2

CBNumber:: CB5155903

Molecular Formula:: C8H16N2O4S2

Molecular Weight:: 268.35

MDL Number:: MFCD00020391

MOL File:: 626-72-2.mol

Last updated:2023-10-27 14:36:51

Request For Quotation

L-Homocystine Properties

Melting point	281-284 °C (dec.)(lit.)
alpha	77 º (c=1% in 1N HCl)
Boiling point	507.6±50.0 °C(Predicted)
Density	1.443±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	H2O : 5 mg/mL (18.63 mM; ultrasonic and adjust pH to 3 with H2O)DMSO : 1 mg/mL (3.73 mM; ultrasonic and adjust pH to 5 with HCl)
form	Powder
pka	1.90±0.10(Predicted)
BRN	1728583
InChIKey	ZTVZLYBCZNMWCF-WDSKDSINSA-N
CAS DataBase Reference	626-72-2(CAS DataBase Reference)
FDA UNII	804AS222UE
EPA Substance Registry System	L-Homocystine (626-72-2)

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3
HS Code	29309090

L-Homocystine price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H6010	L-Homocystine ≥98% (HPLC)	626-72-2	100mg	$121	2024-03-01	Buy
Sigma-Aldrich	H6010	L-Homocystine ≥98% (HPLC)	626-72-2	1g	$597	2024-03-01	Buy
Sigma-Aldrich	H6010	L-Homocystine ≥98% (HPLC)	626-72-2	500mg	$347	2024-03-01	Buy
Usbiological	H7000	L-Homocystine, 99%	626-72-2	1g	$330	2021-12-16	Buy
TRC	H591360	L-Homocystine	626-72-2	10g	$145	2021-12-16	Buy

Product number	Packaging	Price	Buy
H6010	100mg	$121	Buy
H6010	1g	$597	Buy
H6010	500mg	$347	Buy
H7000	1g	$330	Buy
H591360	10g	$145	Buy

L-Homocystine Chemical Properties,Uses,Production

Chemical Properties

L-homocysteine is an aliphatic amino acid with the molecular formula (C8H16N2O4S2). It is a white powder with an acidic taste and is easily soluble in water. It has limited solubility in ethanol. L-homocysteine has a sulfhydryl group on its side chain, which allows it to form disulfide bonds with other L-homocysteine residues in proteins. This feature contributes to the stable three-dimensional structure of proteins. As a result, L-homocysteine finds extensive applications in industries such as pharmaceuticals, food, feed, and cosmetics.

Uses

Increased levels lead to hyperhomocysteinemia; a cardiovascular risk factor in prediction of coronary heart disease as well as being associated with congenital birth defects, pregnancy complications and cancer.

Definition

ChEBI: L,L-homocystine is a homocystine in which both chiral centres have L configuration. It is functionally related to a L-homocysteine. It is a tautomer of a L,L-homocystine zwitterion.

Synthesis

L-homoserine(626-72-2) is biosynthesized from L-aspartate, which is synthesized from oxaloacetate, a TCA cycle intermediate. Homoserine is activated through esterification to form the O-acetyl ester by the enzyme homoserine O-acetyltransferase. In certain organisms, including the yeast Saccharomyces cerevisiae and certain bacteria, hydrogen sulfide reacts with O-acetyl-L-homoserine, replacing the acetyl group and forming L-homocysteine.
L-homocysteine biosynthesis

Purification Methods

The acid (3g) is dissolved in freshly boiled H2O (30mL) under N2, cooled under N2 (all operations should be under N2), absolute EtOH (100mL) is added, the acid is filtered off, and a second crop is obtained by diluting the filtrate to 500mL with absolute EtOH, kept overnight in a refrigerator, filtered, washed with EtOH and dried in a vacuum. The D(R,R)-form has similar properties but is –ve in M HCl and +ve in H2O. [du Vigneaud & Patterson J Biol Chem 109 101 1935, du Vigneaud & Brown Biochemical Preparations 5 93, 95 1975, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2667-2670 1961, Beilstein 4 III 1643, 4 IV 3199, Koegel et al. J Am Chem Soc 77 5708 1955.]

L-Homocystine Preparation Products And Raw materials

Raw materials

L-Homoserine L-aspartic acid, sodium salt (S)-4-ACETOXY-2-AMINO-BUTYRIC ACID homoserine O-acetyltransferase Hydrogen Sulfide

RIBOMINUS(BACTERIA)

1of2

Preparation Products

L-Homocystine Suppliers

Global( 242)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12737	58

Supplier	Advantage
Henan Bao Enluo International TradeCo.，LTD	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Xi'an Kono chem co., Ltd.,	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58
Zhengzhou Alfa Chemical Co.,Ltd	58

View Lastest Price from L-Homocystine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-02	L-Homocystine 626-72-2	US $10.00 / kg	1kg	99%	500t/month	Henan Bao Enluo International TradeCo.，LTD
2023-05-04	L-Homocystine 626-72-2	US $48.00-40.00 / KG	1KG	99%	20tons	Guangzhou Sunton Biotechnology Co., Ltd.
2021-10-14	L-Homocystine 626-72-2	US $0.00 / KG	1KG	98.0%	5000kg/month	WUHAN FORTUNA CHEMICAL CO., LTD

L-Homocystine
626-72-2
US $10.00 / kg
99%
Henan Bao Enluo International TradeCo.，LTD

L-Homocystine
626-72-2
US $48.00-40.00 / KG
99%
Guangzhou Sunton Biotechnology Co., Ltd.

L-Homocystine
626-72-2
US $0.00 / KG
98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

L-Homocystine Spectrum

L-Homocystine(626-72-2)MS L-Homocystine(626-72-2)IR1 L-Homocystine(626-72-2)IR2

626-72-2(L-Homocystine)Related Search:

4-Aminobutyric acid D-2-Aminobutyric acid N-Acetyl-L-cysteine DL-Homocysteine L-Cystine

DL-2-AMINOBUTYRIC ACID L-Cysteine Selenium sulfide DL-3-Aminobutyric acid Cyproterone acetate

Indole-3-butyric acid DL-2-Aminobutyric acid L(+)-2-Aminobutyric acid 3-CARBOXYPROPYL DISULFIDE Butyl disulfide

Methyl propyl disulfide r-Amino Butryric Acid ETHYL PROPYL DISULFIDE

1of4

(2S,2'S)-2,2'-Diamino-(4,4'-dithiobisbutyric acid) 3,3'-(Dithiobismethylene)bisalanine 4,4'-Dithiobis[(2S)-2-aminobutanoic acid] 4,4'-Dithiobis[(S)-2-aminobutanoic acid] 4,4'-Dithiobis[(S)-2-aminobutyric acid] (2S,2'S)-4,4'-Dithiobis[2-aMinobutanoic Acid] [S-(R*,R*)]-4,4'-Dithiobis[2-aMinobutanoic Acid] L-Homocystine ,99% L-Homocystine,L-4,4′-Dithiobis(2-aminobutanoic acid) L-HOMOCYSTINE, >=98% (HPLC) (H-L-HomoCys-OH)2 L-Homocystine≥ 99% (Assay) H-HoCys-OH L-4,4'-Dithiobis(2-aminobutanoic acid) (H-HCY-OH)2 (H-HOCYS-OH)2 (H-HOMOCYS-OH)2 H-L-HOCYSTINE L-4,4'-DITHIO-BIS(2-AMINOBUTANOIC ACID) 4,4’-dithiobis[2-amino-,[s-(theta,theta)]-butanoicaci (H-Hcy-OH)? L-homocystine cell culture tested [S-(R*,R*)]-4,4'-dithiobis[2-aminobutyric] acid 2-amino-4-(3-amino-3-carboxy-propyl)disulfanyl-butanoic acid H-HoCys-OH (H-Hcys-OH) 2 L-Homocystine H-L-HCystine L-Homocystine USP/EP/BP Butanoic acid, 4,4'-dithiobis[2-amino-, (2S,2'S)- (2S)-2-amino-4-{[(3S)-3-amino-3-carboxypropyl]disulfanyl}butanoic acid (2S,2'S)-4,4'-Disulfanediylbis(2-aMinobutanoic acid) L Homocystine,Inhibitor,Endogenous Metabolite,LHomocystine,inhibit,L-Homocystine Vincamine Impurity 1( Vincamine EP Impurity A ) 626-72-2 C8H16N2O4S2 Unnatural Amino Acid Derivatives Specialty Synthesis Peptide Synthesis Homo-Amino Acids Amines Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds Amino Acids