Prasugrel Hydrochloride
- CAS No.
- 389574-19-0
- Chemical Name:
- Prasugrel Hydrochloride
- Synonyms
- Prasugrel HCl;Prasugrenhydrochloride;2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride;Ridomil 72WP;Prasugrel HCI;Unii-G89jq59I13;Effient Hydrochloride;Prasugrel hydrochloric;LY 640315 Hydrochloride;PRASUGREL HYDROCHLORIDE
- CBNumber:
- CB52465251
- Molecular Formula:
- C20H20FNO3S.ClH
- Molecular Weight:
- 409.907
- MDL Number:
- MFCD11867705
- MOL File:
- 389574-19-0.mol
- MSDS File:
- SDS
Melting point | >173?C (dec.) |
---|---|
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
form | Solid |
color | White to Pale Brown |
InChI | InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H |
InChIKey | JALHGCPDPSNJNY-UHFFFAOYSA-N |
SMILES | N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl |
FDA UNII | G89JQ59I13 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
HS Code | 2934990002 |
Prasugrel Hydrochloride price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 1554104 | Prasugrel Hydrochloride United States Pharmacopeia (USP) Reference Standard | 389574-19-0 | 150MG | $715 | 2024-03-01 | Buy |
Usbiological | P5620 | Prasugrel Hydrochloride | 389574-19-0 | 100mg | $262 | 2021-12-16 | Buy |
TRC | P701150 | PrasugrelHydrochloride | 389574-19-0 | 1g | $690 | 2021-12-16 | Buy |
TRC | P701150 | PrasugrelHydrochloride | 389574-19-0 | 10mg | $60 | 2021-12-16 | Buy |
TRC | P701150 | PrasugrelHydrochloride | 389574-19-0 | 50mg | $150 | 2021-12-16 | Buy |
Prasugrel Hydrochloride Chemical Properties,Uses,Production
Description
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation.
Chemical Properties
White to Off-White Solid
Uses
A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome
in vivo
In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM. Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.
Prasugrel Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Beijing Hope Pharmaceutical Co., Ltd. | +86-010-67886402 +8613611125266 | market@hopelife.cn | China | 71 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12468 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 3001 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
View Lastest Price from Prasugrel Hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-22 | PRASUGREL HYDROCHLORIDE
389574-19-0
|
US $50.00 / kg | 1kg | 99.10% | 50000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | ||
2023-09-08 | Prasugrel hydrochloride
389574-19-0
|
US $0.00 / KG Ton | 1KG Ton | 99.5%+ | 2 tons/month | Zhuhai Hairuide Bioscience and Technology Co., Ltd | ||
2023-08-31 | Prasugrel hydrochloride
389574-19-0
|
US $100.00 / bag | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD |
- PRASUGREL HYDROCHLORIDE
389574-19-0
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
- Prasugrel hydrochloride
389574-19-0
- US $0.00 / KG Ton
- 99.5%+
- Zhuhai Hairuide Bioscience and Technology Co., Ltd
- Prasugrel hydrochloride
389574-19-0
- US $100.00 / bag
- 99
- Hebei Fengqiang Trading Co., LTD