ZLJ-6
- CAS No.
- 1051931-39-5
- Chemical Name:
- ZLJ-6
- Synonyms
- ZLJ-6;ZLJ-6 Exclusive;QEJPXTVPNIOEHZ-VEZAGKLZSA-N
- CBNumber:
- CB52592894
- Molecular Formula:
- C13H17N3O6S2
- Molecular Weight:
- 375.421
- MDL Number:
- MFCD18428018
- MOL File:
- 1051931-39-5.mol
ZLJ-6 price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 13271 | ZLJ-6 ≥98% | 1051931-39-5 | 1mg | $39 | 2024-03-01 | Buy |
Cayman Chemical | 13271 | ZLJ-6 ≥98% | 1051931-39-5 | 5mg | $172 | 2024-03-01 | Buy |
Cayman Chemical | 13271 | ZLJ-6 ≥98% | 1051931-39-5 | 10mg | $302 | 2024-03-01 | Buy |
Cayman Chemical | 13271 | ZLJ-6 ≥98% | 1051931-39-5 | 25mg | $660 | 2024-03-01 | Buy |
ApexBio Technology | C4357 | ZLJ-6 | 1051931-39-5 | 25mg | $753 | 2021-12-16 | Buy |
ZLJ-6 Chemical Properties,Uses,Production
Description
ZLJ-
in vitro
zlj-6 was identified as a potent inhibitor of cyclooxygenase in human whole blood. it also inhibited the production of thromboxane b(2) and prostaglandin e(2) in calcium ionophore a23187-induced human and rat whole blood, and rat peritoneal leukocytes. zlj-6 suppressed the activity of 5-lipoxygenase in the rat basophilic leukemia (rbl-1) cell lysate and in intact cells and reduced the generation of leukotriene b(4) (ltb(4)) in a23187-stimulated human or rat whole blood, and rat peritoneal leukocytes [1].
in vivo
orally administered zlj-6 demonstrated potent anti-inflammatory activity in the carrageenin-induced paw oedema model in rats and showed analgesic activity in the acetic acid-induced abdominal construction model in mice. no gastrointestinal ulcers were found with the anti-inflammatory dose (30 mg/kg) in normal rats [1].
IC 50
0.73, 0.31, and 0.99 μm for cox-1, cox-2, and 5-lo, respectively
References
[1] li, l. ,ji, h.,sheng, l., et al. the anti-inflammatory effects of zlj-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. european journal of pharmacology 607 (1-3), 244-250 (2009).
ZLJ-6 Preparation Products And Raw materials
Raw materials
Preparation Products
ZLJ-6 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |