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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine

CAS No.
1638499-31-6
Chemical Name:
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
Synonyms
Tofacitinib-4;Tofatinib Impurity 35;Nicotinamide Impurity 114;3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)-;(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine? (Tofacitinib Impurity);Tofacitinib impurity 3/(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride
CBNumber:
CB53154815
Molecular Formula:
C14H22N2
Molecular Weight:
218.34
MDL Number:
MFCD25372053
MOL File:
1638499-31-6.mol
Last updated:2023-05-15 10:43:34

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Properties

Boiling point 302.6±35.0 °C(Predicted)
Density 1.00±0.1 g/cm3(Predicted)
pka 10.26±0.40(Predicted)

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B276215 (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine 1638499-31-6 2.5mg $330 2021-12-16 Buy
TRC B276215 (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine 1638499-31-6 25mg $2640 2021-12-16 Buy
Product number Packaging Price Buy
B276215 2.5mg $330 Buy
B276215 25mg $2640 Buy

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Chemical Properties,Uses,Production

Uses

(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 32)Suppliers
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Standardpharm Co. Ltd.
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BOC Sciences
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Shanghai Payne Pharmaceutical Technology Co.Ltd
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Beijing Comparison Pharmaceutical Technology Co., Ltd 010-52878169 15701683040 sales@bjcomparison.com China 4681 58
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BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shijiazhuang yaoBo Pharmaceutical Co., Ltd. 15633056635 2880679888@qq.com China 2684 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131981 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 7851 55
Tofacitinib-4 Tofacitinib impurity 3/(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine? (Tofacitinib Impurity) 3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)- Tofatinib Impurity 35 Nicotinamide Impurity 114 1638499-31-6