Aprepitant Impurity 9

CAS No.
219821-37-1
Chemical Name:
Aprepitant Impurity 9
Synonyms
Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber:
CB53358992
Molecular Formula:
C24H25F7N4O4
Molecular Weight:
566.47
MDL Number:
MOL File:
219821-37-1.mol
Last updated:2023-05-15 10:44:00

Aprepitant Impurity 9 Properties

Density 1.43±0.1 g/cm3(Predicted)
solubility soluble in Chloroform, Dichloromethane, Methanol
form Solid
pka 7.86±0.43(Predicted)
color Pale-Yellow
FDA UNII TQ265G4AMC

Aprepitant Impurity 9 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D297840 N-(Destriazolonomethyl)N-(Methylcarboxyacetamidohydrazono)Aprepitant 219821-37-1 10mg $1010 2021-12-16 Buy
Product number Packaging Price Buy
D297840 10mg $1010 Buy

Aprepitant Impurity 9 Chemical Properties,Uses,Production

Uses

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 Preparation Products And Raw materials

Raw materials

Preparation Products

Aprepitant Impurity 9 Suppliers

Global( 37)Suppliers
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Standardpharm Co. Ltd.
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ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17993 56
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Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9843 12
Aprepitant Impurity 9 Aprepitant Open-Ring Methyl Ester Impurity 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity Aprepitant Impurity 47 Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate Fosaprepitant Impurity U 219821-37-1 C24H25F7N4O4