ChemicalBook >> CAS DataBase List >>Indobufen
Indobufen
- CAS No.
- 63610-08-2
- Chemical Name:
- Indobufen
- Synonyms
- 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid;d-INB;K 2930;K-3920;Ibustrin;INDOBUFEN;INDOBNFEN;lndobufen;d-Indobufen;Indobuprofen
- CBNumber:
- CB6213695
- Molecular Formula:
- C18H17NO3
- Molecular Weight:
- 295.34
- MDL Number:
- MFCD00572250
- MOL File:
- 63610-08-2.mol
Last updated:2024-04-07 18:44:46
| Melting point | 182-184° |
|---|---|
| Boiling point | 518.1±50.0 °C(Predicted) |
| Density | 1.275±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.39±0.10(Predicted) |
| color | White |
| InChI | InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22) |
| InChIKey | AYDXAULLCROVIT-UHFFFAOYSA-N |
| SMILES | O=C1C2C=CC=CC=2CN1C1C=CC(C(CC)C(=O)O)=CC=1 |
| CAS DataBase Reference | 63610-08-2(CAS DataBase Reference) |
| FDA UNII | 6T9949G4LZ |
| ATC code | B01AC10 |
| EPA Substance Registry System | Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-.alpha.-ethyl- (63610-08-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
Indobufen price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | I576500 | Indobufen | 63610-08-2 | 25mg | $70 | 2021-12-16 | Buy |
| ChemScene | CS-0014291 | Indobufen 99.98% | 63610-08-2 | 5mg | $60 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004904 | INDOBUFEN 95.00% | 63610-08-2 | 25MG | $288.75 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 46849 | Indobufen | 63610-08-2 | 100mg | $640 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004904 | INDOBUFEN 95.00% | 63610-08-2 | 100MG | $739.2 | 2021-12-16 | Buy |
Indobufen Chemical Properties,Uses,Production
Description
Indobufen is a platelet aggregation inhibitor related to the antiinflammatory agent indoprofen. It has shown clinical efficacy in peripheral artery disease, in prevention of deep vein thrombosis after myocardial infarction, and in blocking excercise-induced increase in platelet aggregation in angina patients.
Originator
Erbamont (Italy)
Uses
Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.
Definition
ChEBI: Indobufen is a member of isoindoles.
brand name
IBUSTRIN
Clinical Use
A reversible but very potent inhibitor of platelet COX-1 activity, was shown to have comparable clinical efficacy to that of aspirin in prevention of DVT after myocardial infarction and in blocking exercise-induced increase in platelet aggregation. In the secondary prevention of thromboembolic events, 100 or 200 mg of indobufen twice daily is as effective as warfarin or aspirin in patients with or without atrial fibrillation. Currently, indobufen is only available for routine clinical use in Europe.
Synthesis of Indobufen from Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-, ethyl ester
Indobufen Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 215)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 | guoyuan@eastchinapharm.com | China | 1615 | 58 |
| Jewim Pharmaceutical (Shandong) Co., Ltd. | +86-15552509998 +86-15621883869 | liutf@jewim.com.cn | China | 251 | 58 |
| Beijing Hope Pharmaceutical Co., Ltd. | +86-010-67886402 +8613611125266 | market@hopelife.cn | China | 71 | 58 |
| Changzhou Rokechem Technology Co., Ltd. | 18758118018 | sales001@rokechem.com | China | 255 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales05@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
View Lastest Price from Indobufen manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-13 | Indobufen
63610-08-2
|
US $95.00-85.00 / kilograms | 1kilograms | 99% | 100tons | Hebei Dangtong Import and export Co LTD | |
 |
2024-05-10 | Indobufen
63610-08-2
|
US $65.00-650.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2024-04-07 | Indobufen
63610-08-2
|
US $0.00-0.00 / g | 1g | 99.9% | 20tons | airuikechemical co., ltd. |
63610-08-2(Indobufen)Related Search:
1-Oxo-2-[p-[(α-ethyl)carboxyMethyl]phenyl]isoindoline
2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric Acid
K 2930
(+-)-butyricaci
1-oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline
4-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-alpha-ethyl-benzeneaceticacid
2-[4-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PHENYL]-BUTYRIC ACID
lndobufen
INDOBNFEN
INDOBUFEN
2-[4-(1-oxo-2-isoindolinyl)phenyl]butyric acid
(2R)-2-[4-(3-Oxo-1H-isoindol-2-yl)phenyl]butanoic acid
1-Oxo-2-(p-((a-ethyl)carboxymethyl)phenyl)isoindoline
4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)a-ethyl-benzeneacetic acid
Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-a-ethyl-
Butyric acid, 2-(p-(1-oxo-2-isoindolinyl)phenyl)-, (+-)
(±)-4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid
(αR)-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid
[R,(-)]-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid
(αS)-4-[(1,3-Dihydro-1-oxo-2H-isoindol)-2-yl]-α-ethylbenzeneacetic acid
d-INB
d-Indobufen
Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-alpha-ethyl-
Ibustrin
K-3920
Ibustrin， K 3920
Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-
Indobufen USP/EP/BP
63610-08-2,Indobufen
(2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid
2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid
Indole cloth Finn
Indobufen WRS
2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoicaci
Indobuprofen
63610-08-2
Amines
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
63610-08-2