10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester

CAS No.
3148-42-3
Chemical Name:
10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester
Synonyms
Rauvanin;Rauvanine;10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester;Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (19β)-
CBNumber:
CB62277929
Molecular Formula:
C23H28N2O5
Molecular Weight:
412.48
MDL Number:
MOL File:
3148-42-3.mol

10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester Properties

Melting point 129-135°C (dec.).

10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester Chemical Properties,Uses,Production

Description

This yohimbine type alkaloid is a constituent of Rauwolfia vomitora and may be purified by recrystallization from MeOH when it forms colourless leaflets of the hemihydrate. It yields crystalline salts, e.g. the hydrochloride, m.p. 280-2°C and the tartrate, m.p. 215-6° C (dec.). The alkaloid is dextrorotatory with [α]D + 32.5° (c 1.0, CHC13). The structure is that of 10-methoxyraunitidine.

References

Goutarel, Gut, Parello., Compt. rend., 253, 2589 (1961)
Finch et al., Tetrahedron, 22, 1327 (1966)

10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester Suppliers

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10,11-Dimethoxy-19β-methyl-16,17-didehydro-18-oxayohimban-16-carboxylic acid methyl ester Rauvanin Rauvanine Oxayohimban-16-carboxylic acid, 16,17-didehydro-10,11-dimethoxy-19-methyl-, methyl ester, (19β)- 3148-42-3