ChemicalBook >> CAS DataBase List >>Edoxaban-d6
Edoxaban-d6
- CAS No.
- 1304701-57-2
- Chemical Name:
- Edoxaban-d6
- Synonyms
- Edoxaban-d6;[2H6]-Edoxaban;Edoxaban hydrochloride salt;2H6]-Edoxaban hydrochloride salt;N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
- CBNumber:
- CB63163409
- Molecular Formula:
- C24H30ClN7O4S
- Molecular Weight:
- 548.06
- MDL Number:
- MFCD32661438
- MOL File:
- 1304701-57-2.mol
Last updated:2023-06-08 09:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P501 | |||||||||
| NFPA 704 |
|
Edoxaban-d6 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 25760 | Edoxaban-d6 ≥99% deuterated forms (d1-d6) | 1304701-57-2 | 500μg | $396 | 2024-03-01 | Buy |
| Cayman Chemical | 25760 | Edoxaban-d6 ≥99% deuterated forms (d1-d6) | 1304701-57-2 | 1mg | $711 | 2024-03-01 | Buy |
| Usbiological | 448076 | Edoxaban-d6 | 1304701-57-2 | 500ug | $531 | 2021-12-16 | Buy |
| TRC | E555522 | Edoxaban-d6 | 1304701-57-2 | 5mg | $1850 | 2021-12-16 | Buy |
| AK Scientific | 4287DK | N-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide | 1304701-57-2 | 1mg | $889 | 2021-12-16 | Buy |
Edoxaban-d6 Chemical Properties,Uses,Production
Description
Edoxaban-d6 is intended for use as an internal standard for the quantification of edoxaban by GC- or LC-MS. Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma. Oral administration of edoxaban (0.5-12.5 mg/kg) reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis. It also reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis. Formulations containing edoxaban have been used to prevent stroke in patients with atrial fibrillation.
Uses
Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.
Edoxaban-d6 Preparation Products And Raw materials
Raw materials
Preparation Products
Edoxaban-d6 Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6854 | 65 |
| Clearsynth Canada Inc. | +1.415.685.4395 | enquiry@clearsynth.com | Canada | 912 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 | amber@biochempartner.com | China | 3063 | 58 |
| Shenzhen Popeye Biotechnology Co. Ltd. | 0755-86320212 | popeye02@qq.com | China | 310 | 58 |
| Jinan blalong chemical co. LTD | 2710913286@.com | 1513643261@qq.com | China | 14253 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shenzhen ruikai de biotechnology co., ltd. | 0755-61348847 17820674378 | 2682116078@qq.com | China | 7844 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | 12345678910 | nanfengdrug@163.com | China | 15323 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Shanghai Ruipu Medical Technology Co., Ltd | 15895968936 | 1018762393@qq.com | China | 9935 | 58 |
1304701-57-2(Edoxaban-d6)Related Search:
2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid
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EthanediaMide, N1-(5-chlo...
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EthanediaMide, N1-(5-chlo...
Edoxaban Impurity 16
(1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester
EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]-
(1S,3R,4S)-4-(2-((5-chloropyridin-
2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid
(1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester
1of4
Edoxaban-d6
N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
[2H6]-Edoxaban
Edoxaban hydrochloride salt
2H6]-Edoxaban hydrochloride salt
1304701-57-2