8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID
- CAS No.
- 28872-28-8
- Chemical Name:
- 8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID
- Synonyms
- JACARIC ACID;8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID;(8E,10Z,12Z)-Octadeca-8,10,12-trienoic acid;8,10,12-Octadecatrienoic acid, (8Z,10E,12Z)-
- CBNumber:
- CB6347888
- Molecular Formula:
- C18H30O2
- Molecular Weight:
- 278.43
- MDL Number:
- MFCD05864027
- MOL File:
- 28872-28-8.mol
| Boiling point | 423.4±24.0 °C(Predicted) |
|---|---|
| Density | 0.924±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, Light sensitive |
| solubility | Ethanol (Soluble) |
| pka | 4.77±0.10(Predicted) |
| form | Colourless Solution |
| Stability | Light Sensitive |
| FDA UNII | APY53D8J4D |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H350 | |||||||||
| Precautionary statements | P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16036 | Jacaric Acid ≥95% | 28872-28-8 | 1mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 16036 | Jacaric Acid ≥95% | 28872-28-8 | 5mg | $543 | 2024-03-01 | Buy |
| Cayman Chemical | 16036 | Jacaric Acid ≥95% | 28872-28-8 | 10mg | $961 | 2024-03-01 | Buy |
| TRC | J210380 | JacaricAcid | 28872-28-8 | 25mg | $1485 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000713 | 8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID 95.00% | 28872-28-8 | 25MG | $1110.88 | 2021-12-16 | Buy |
8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID Chemical Properties,Uses,Production
Description
Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Structurally, it is an 18-carbon ω-6 triene isomer of γ-linolenic acid . Jacaric acid induces cell cycle arrest and apoptosis in a variety of cancer cell lines (GI50 = 1-5 μM). It increases the production of reactive oxygen species, and cytotoxicity is abolished by the antioxidant α-tocopherol, suggesting that apoptosis results from oxidative stress. Jacaric acid is metabolized in vivo to conjugated linoleic acid (Item No. 90140), which is also cytotoxic to cancer cells. Jacaric acid inhibits cyclooxygenase-1 in vitro (Ki = 1.7 μM) and, with long term feeding, decreases stearoyl-CoA desaturase expression and activity in mice.
Uses
Jacaric Acid (10mg/mL in Ethanol) is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants.
Uses
8(Z),10(E),12(Z)-Octadecatrienoic Acid, is a conjugated Linoleic Acid, a compound that has reported to exhibit anticarcinogenic activity. Also a potent antioxidant.
Definition
ChEBI: 8Z,10E,12Z-octadecatrienoic acid is an octadecatrienoic acid.
8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
8(Z),10(E),12(Z)-OCTADECATRIENOIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| MedBioPharmaceutical Technology Inc | 58 |
| Energy Chemical | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |