ChemicalBook >> CAS DataBase List >>Boc-Val-Ala-PAB-PNP
Boc-Val-Ala-PAB-PNP
- CAS No.
- 1884578-00-0
- Chemical Name:
- Boc-Val-Ala-PAB-PNP
- Synonyms
- Boc-Val-Ala-PAB-PNP;Boc-Val-Ala-PAB-PNP USP/EP/BP;4-[(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]propanamido]benzyl (4-Nitrophenyl) Carbonate;L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;tert-Butyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)carbamate
- CBNumber:
- CB65864429
- Molecular Formula:
- C27H34N4O9
- Molecular Weight:
- 558.58
- MDL Number:
- MFCD28557281
- MOL File:
- 1884578-00-0.mol
Last updated:2024-03-29 18:52:01
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319 |
Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Boc-Val-Ala-PAB-PNP price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Iris Biotech GmbH | ADC1050 | Boc-Val-Ala-PAB-PNP | 1884578-00-0 | 100mg | $168.75 | 2021-12-16 | Buy |
Iris Biotech GmbH | ADC1050 | Boc-Val-Ala-PAB-PNP | 1884578-00-0 | 250mg | $337.5 | 2021-12-16 | Buy |
Iris Biotech GmbH | ADC1050 | Boc-Val-Ala-PAB-PNP | 1884578-00-0 | 1g | $1012.5 | 2021-12-16 | Buy |
Boc-Val-Ala-PAB-PNP Chemical Properties,Uses,Production
Uses
Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
In vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Description
Boc-Val-Ala-PAB-PNP can be used to design cleavable ADC linkers. The Val-Ala, as shown in the ACD Zynlonta, is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Boc-Val-Ala-PAB-PNP Preparation Products And Raw materials
Raw materials
Preparation Products
Boc-Val-Ala-PAB-PNP Suppliers
Global( 32)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2893 | 58 |
Tianjin Chempharmatech Co.,Ltd. | 022-66211079 13212288319 | sales@chempharmatech.com | China | 806 | 55 |
Shanghai Send Pharmaceutical Technology Co., Ltd. | 021-50266790 Q3382968513 | Hailey@shsendpharm.com | China | 3170 | 55 |
ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
Heze Development Zone chuangli Chemical Co., Ltd. | +86-530-529 6766,+86-15666160102 15666160102 | info@chuangli-chem.com | China | 877 | 55 |
View Lastest Price from Boc-Val-Ala-PAB-PNP manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-03-29 | Boc-Val-Ala-PAB-PNP
1884578-00-0
|
US $0.00 / g | 1g | >95.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
- Boc-Val-Ala-PAB-PNP
1884578-00-0
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
Boc-Val-Ala-PAB-PNP
L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
Boc-Val-Ala-PAB-PNP USP/EP/BP
4-[(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]propanamido]benzyl (4-Nitrophenyl) Carbonate
tert-Butyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)carbamate
1884578-00-0
ADC LINKER
Linker