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Boc-Val-Ala-PAB-PNP

CAS No.
1884578-00-0
Chemical Name:
Boc-Val-Ala-PAB-PNP
Synonyms
Boc-Val-Ala-PAB-PNP;Boc-Val-Ala-PAB-PNP USP/EP/BP;4-[(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]propanamido]benzyl (4-Nitrophenyl) Carbonate;L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;tert-Butyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)carbamate
CBNumber:
CB65864429
Molecular Formula:
C27H34N4O9
Molecular Weight:
558.58
MDL Number:
MFCD28557281
MOL File:
1884578-00-0.mol
Last updated:2024-03-29 18:52:01

Boc-Val-Ala-PAB-PNP Properties

Boiling point 793.1±60.0 °C(Predicted)
Density 1.269±0.06 g/cm3(Predicted)
pka 11.26±0.46(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Boc-Val-Ala-PAB-PNP price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Iris Biotech GmbH ADC1050 Boc-Val-Ala-PAB-PNP 1884578-00-0 100mg $168.75 2021-12-16 Buy
Iris Biotech GmbH ADC1050 Boc-Val-Ala-PAB-PNP 1884578-00-0 250mg $337.5 2021-12-16 Buy
Iris Biotech GmbH ADC1050 Boc-Val-Ala-PAB-PNP 1884578-00-0 1g $1012.5 2021-12-16 Buy
Product number Packaging Price Buy
ADC1050 100mg $168.75 Buy
ADC1050 250mg $337.5 Buy
ADC1050 1g $1012.5 Buy

Boc-Val-Ala-PAB-PNP Chemical Properties,Uses,Production

Uses

Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

In vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Description

Boc-Val-Ala-PAB-PNP can be used to design cleavable ADC linkers. The Val-Ala, as shown in the ACD Zynlonta, is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Boc-Val-Ala-PAB-PNP Preparation Products And Raw materials

Raw materials

Preparation Products

Boc-Val-Ala-PAB-PNP Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29067 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2893 58
Tianjin Chempharmatech Co.,Ltd. 022-66211079 13212288319 sales@chempharmatech.com China 806 55
Shanghai Send Pharmaceutical Technology Co., Ltd. 021-50266790 Q3382968513 Hailey@shsendpharm.com China 3170 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Heze Development Zone chuangli Chemical Co., Ltd. +86-530-529 6766,+86-15666160102 15666160102 info@chuangli-chem.com China 877 55

View Lastest Price from Boc-Val-Ala-PAB-PNP manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Val-Ala-PAB-PNP pictures 2024-03-29 Boc-Val-Ala-PAB-PNP
1884578-00-0
US $0.00 / g 1g >95.00% 1g Xian confluore Biological Technology Co., Ltd.
  • Boc-Val-Ala-PAB-PNP pictures
  • Boc-Val-Ala-PAB-PNP
    1884578-00-0
  • US $0.00 / g
  • >95.00%
  • Xian confluore Biological Technology Co., Ltd.
Boc-Val-Ala-PAB-PNP L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- Boc-Val-Ala-PAB-PNP USP/EP/BP 4-[(S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]propanamido]benzyl (4-Nitrophenyl) Carbonate tert-Butyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)carbamate 1884578-00-0 ADC LINKER Linker