2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole
- CAS No.
- 6649-90-7
- Chemical Name:
- 2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole
- Synonyms
- TaClo;1,2,3,4-Tetrahydro-1-(trichloromethyl)-β-carboline;1-(Trichloromethyl)-1,2,3,4-tetrahydro-β-carboline;rac 1-TrichloroMethyl-1,2,3,4-Tetrahydro-β-carboline;2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole;1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1-(trichloromethyl)-
- CBNumber:
- CB72271065
- Molecular Formula:
- C12H11Cl3N2
- Molecular Weight:
- 289.59
- MDL Number:
- MFCD09971793
- MOL File:
- 6649-90-7.mol
Last updated:2023-04-23 13:52:06
Melting point | >132°C (dec.) |
---|---|
Boiling point | 447.4±40.0 °C(Predicted) |
Density | 1.480±0.06 g/cm3(Predicted) |
storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | Ethyl Acetate (Slightly), Methanol (Slightly) |
pka | 16.74±0.40(Predicted) |
form | Solid |
color | Beige |
2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole Chemical Properties,Uses,Production
Uses
1-Trichloromethyl-1,2,3,4-Tetrahydro-β-carboline (TaClo) is a dopaminergic and serotonergic neurotoxin. Liver enzymes produces TaClo via catalysis reaction of Tricloroethane with Tryptamine (T894600). TaClo destroys dopamine-producing cells and is structurally similar to the dopaminergic neurotoxin MPTP. As a result, TaClo is a molecule of importance in the study of Parkinson’s disease.
2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole Suppliers
Global( 7)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55954 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
Supplier | Advantage |
---|---|
J & K SCIENTIFIC LTD. | 76 |
Chemsky (shanghai) International Co.,Ltd | 60 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | 58 |
Energy Chemical | 58 |
1-(Trichloromethyl)-1,2,3,4-tetrahydro-β-carboline
1,2,3,4-Tetrahydro-1-(trichloromethyl)-β-carboline
2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole
TaClo
rac 1-TrichloroMethyl-1,2,3,4-Tetrahydro-β-carboline
1H-Pyrido[3,4-b]indole, 2,3,4,9-tetrahydro-1-(trichloromethyl)-
6649-90-7
C12H11Cl3N2
Intermediates & Fine Chemicals
Neurochemicals
Pharmaceuticals
Aromatics
Heterocycles